Literature DB >> 24581486

Nuclear pores set the speed limit for mitosis.

Abigail Buchwalter1, Martin W Hetzer2.   

Abstract

The spindle assembly checkpoint prevents separation of sister chromatids until each kinetochore is attached to the mitotic spindle. Rodriguez-Bravo et al. report that the nuclear pore complex scaffolds spindle assembly checkpoint signaling in interphase, providing a store of inhibitory signals that limits the speed of the subsequent mitosis.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24581486      PMCID： PMC4008093          DOI： 10.1016/j.cell.2014.02.004

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

1.  Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.

Authors:  R Fraschini; A Beretta; L Sironi; A Musacchio; G Lucchini; S Piatti
Journal:  EMBO J       Date:  2001-12-03       Impact factor: 11.598

2.  Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.

Authors:  Lucia Sironi; Marina Mapelli; Stefan Knapp; Anna De Antoni; Kuan-Teh Jeang; Andrea Musacchio
Journal:  EMBO J       Date:  2002-05-15       Impact factor: 11.598

3.  Timing and checkpoints in the regulation of mitotic progression.

Authors:  Patrick Meraldi; Viji M Draviam; Peter K Sorger
Journal:  Dev Cell       Date:  2004-07       Impact factor: 12.270

Review 4.  Gene regulation by nucleoporins and links to cancer.

Authors:  Alwin Köhler; Ed Hurt
Journal:  Mol Cell       Date:  2010-04-09       Impact factor: 17.970

5.  Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor.

Authors:  Veronica Rodriguez-Bravo; John Maciejowski; Jennifer Corona; Håkon Kirkeby Buch; Philippe Collin; Masato T Kanemaki; Jagesh V Shah; Prasad V Jallepalli
Journal:  Cell       Date:  2014-02-27       Impact factor: 41.582

6.  Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint.

Authors:  Sang Hyun Lee; Harry Sterling; Alma Burlingame; Frank McCormick
Journal:  Genes Dev       Date:  2008-11-01       Impact factor: 11.361

7.  Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.

Authors:  John Maciejowski; Kelly A George; Marie-Emilie Terret; Chao Zhang; Kevan M Shokat; Prasad V Jallepalli
Journal:  J Cell Biol       Date:  2010-07-12       Impact factor: 10.539

Review 8.  The spindle-assembly checkpoint in space and time.

Authors:  Andrea Musacchio; Edward D Salmon
Journal:  Nat Rev Mol Cell Biol       Date:  2007-04-11       Impact factor: 94.444

9.  The spindle assembly checkpoint works like a rheostat rather than a toggle switch.

Authors:  Philippe Collin; Oxana Nashchekina; Rachael Walker; Jonathon Pines
Journal:  Nat Cell Biol       Date:  2013-10-06       Impact factor: 28.824

10.  Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.

Authors:  Nina Schweizer; Cristina Ferrás; David M Kern; Elsa Logarinho; Iain M Cheeseman; Helder Maiato
Journal:  J Cell Biol       Date:  2013-12-23       Impact factor: 10.539
  10 in total
  4 in total

1.  Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A.

Authors:  Akiko Kobayashi; Chieko Hashizume; Takayuki Dowaki; Richard W Wong
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

Review 2.  What Are the Potential Roles of Nuclear Perlecan and Other Heparan Sulphate Proteoglycans in the Normal and Malignant Phenotype.

Authors:  Anthony J Hayes; James Melrose
Journal:  Int J Mol Sci       Date:  2021-04-23       Impact factor: 5.923

3.  Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction.

Authors:  Firli R P Dewi; Takahiro Domoto; Masaharu Hazawa; Akiko Kobayashi; Takayuki Douwaki; Toshinari Minamoto; Richard W Wong
Journal:  Oncotarget       Date:  2018-01-30

4.  PTEN regulates spindle assembly checkpoint timing through MAD1 in interphase.

Authors:  Yu Liu; Xiao Du; Shuting Zhang; Yang Liu; Qiaoling Zhang; Qi Yin; Michael A McNutt; Yuxin Yin
Journal:  Oncotarget       Date:  2017-08-24
  4 in total

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