Literature DB >> 2457983

Interferons as gene activators: close linkage of two interferon-activatable murine genes.

D A Engel1, J Snoddy, E Toniato, P Lengyel.   

Abstract

Previously we have identified a mouse genomic clone (clone 5) which specifies the 5' flanking region and the 5' terminal exon of an interferon-activatable gene (202 gene). Here, we show that about 5 kb upstream from this flanking region in clone 5 there occurs a 3' terminal region of a second interferon-activatable gene (203 gene). The two genes are transcribed in the same direction. Segments from the 203 gene can be hybridized to a set of five interferon-inducible RNAs. The 203 mRNAs are induced about 15-fold in interferon-treated Ehrlich ascites tumor cells.

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Year:  1988        PMID： 2457983     DOI： 10.1016/0042-6822(88)90142-0

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  9 in total

1.  Expression of IFI 16 in epithelial cells and lymphoid tissues.

Authors:  Wu Wei; Christopher J P Clarke; Gino R Somers; Kim S Cresswell; Kate A Loveland; Joseph A Trapani; Ricky W Johnstone
Journal:  Histochem Cell Biol       Date:  2002-12-20       Impact factor: 4.304

Review 2.  Interferon receptors and their role in interferon action.

Authors:  S E Grossberg; J L Taylor; V M Kushnaryov
Journal:  Experientia       Date:  1989-06-15

3.  Wanderings in biochemistry.

Authors:  Peter Lengyel
Journal:  J Biol Chem       Date:  2014-05-27       Impact factor: 5.157

4.  The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression.

Authors:  M J Dawson; J A Trapani; R C Briggs; J K Nicholl; G R Sutherland; E Baker
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

5.  Physical mapping of a family of interferon-activated genes, serum amyloid P-component, and alpha-spectrin on mouse chromosome 1.

Authors:  S F Kingsmore; J Snoddy; D Choubey; P Lengyel; M F Seldin
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

6.  A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-gamma in myeloid cells.

Authors:  J A Trapani; K A Browne; M J Dawson; R G Ramsay; R L Eddy; T B Show; P C White; B Dupont
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

7.  A collection of mRNA species that are inducible in the RAW 264.7 mouse macrophage cell line by gamma interferon and other agents.

Authors:  J M Farber
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

8.  Genomic organization of IFI16, an interferon-inducible gene whose expression is associated with human myeloid cell differentiation: correlation of predicted protein domains with exon organization.

Authors:  J A Trapani; M Dawson; V A Apostolidis; K A Browne
Journal:  Immunogenetics       Date:  1994       Impact factor: 2.846

9.  Interferon action: nucleolar and nucleoplasmic localization of the interferon-inducible 72-kD protein that is encoded by the Ifi 204 gene from the gene 200 cluster.

Authors:  D Choubey; P Lengyel
Journal:  J Cell Biol       Date:  1992-03       Impact factor: 10.539
  9 in total

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