Literature DB >> 24578740

Testosterone deficiency syndrome and cardiovascular health: An assessment of beliefs, knowledge and practice patterns of general practitioners and cardiologists in Victoria, BC.

Christopher J D Wallis1, Hilary Brotherhood2, Peter J Pommerville2.   

Abstract

INTRODUCTION: Testosterone deficiency syndrome (TDS) has been shown to be an independent cardiovascular risk factor and a predisposing factor for metabolic syndrome. As general practitioners and cardiologists primarily care for these patients, we sought to assess their knowledge, beliefs and practice patterns with respect to TDS and cardiac health.
METHODS: We distributed a questionnaire to all 20 cardiologists and a cohort of 128 family practitioners in Victoria, British Columbia. Of the 13 questions, 10 assessed knowledge and beliefs on TDS and 3 assessed current practice patterns.
RESULTS: Most respondents believed that TDS is a medical condition (66.7%) and could negatively affect body composition (62%), but a similar majority was unsure whether it was a cardiac risk factor (66.7%). While most believed that testosterone replacement therapy (TRT) could improve exercise tolerance (62%), most were unsure if it was beneficial in cardiac patients. Cardiologists were significantly less likely to believe that TRT was beneficial in preventing recurrent myocardial infarction and improving myocardial perfusion (p = 0.0133, 0.00186, respectively). The vast majority (88%) did not screen cardiac patients for TDS. If a patient was identified as having TDS, only10% of those surveyed would refer these patients to a urologist.
CONCLUSION: Despite its prevalence in cardiac patients, TDS is not well-understood by general practitioners and cardiologists; they lack knowledge on its deleterious cardiovascular effects. In their role as men's health advocates, urologists should educate our colleagues regarding the correlation between TDS and cardiovascular mortality and risk factors. Limitations of this study include small sample size and restricted geographic scope.

Entities:  

Year:  2014        PMID: 24578740      PMCID: PMC3929476          DOI: 10.5489/cuaj.1448

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  31 in total

1.  Increased carotid atherosclerosis in andropausal middle-aged men.

Authors:  Juuso Mäkinen; Mikko J Järvisalo; Pasi Pöllänen; Antti Perheentupa; Kerttu Irjala; Markku Koskenvuo; Juha Mäkinen; Ilpo Huhtaniemi; Olli T Raitakari
Journal:  J Am Coll Cardiol       Date:  2005-05-17       Impact factor: 24.094

2.  Insulin sensitivity during combined androgen blockade for prostate cancer.

Authors:  Matthew R Smith; Hang Lee; David M Nathan
Journal:  J Clin Endocrinol Metab       Date:  2006-01-24       Impact factor: 5.958

3.  Effects of the luteinizing hormone-releasing hormone agonist leuprolide on lipoproteins, fibrinogen and plasminogen activator inhibitor in patients with benign prostatic hyperplasia.

Authors:  L M Eri; P Urdal; A G Bechensteen
Journal:  J Urol       Date:  1995-07       Impact factor: 7.450

Review 4.  Testosterone and metabolic syndrome: a meta-analysis study.

Authors:  Giovanni Corona; Matteo Monami; Giulia Rastrelli; Antonio Aversa; Yuliya Tishova; Farid Saad; Andrea Lenzi; Gianni Forti; Edoardo Mannucci; Mario Maggi
Journal:  J Sex Med       Date:  2010-08-30       Impact factor: 3.802

Review 5.  Androgen deprivation therapy, insulin resistance, and cardiovascular mortality: an inconvenient truth.

Authors:  Shehzad Basaria
Journal:  J Androl       Date:  2008-06-20

6.  Causes of death in men undergoing androgen suppression therapy for newly diagnosed localized or recurrent prostate cancer.

Authors:  Anthony V D'Amico; Ming-Hui Chen; Andrew A Renshaw; Marian Loffredo; Philip W Kantoff
Journal:  Cancer       Date:  2008-12-15       Impact factor: 6.860

7.  Aging, androgens, and the metabolic syndrome in a longitudinal study of aging.

Authors:  Annabelle Rodriguez; Denis C Muller; E Jeffrey Metter; Marcello Maggio; S Mitchell Harman; Marc R Blackman; Reubin Andres
Journal:  J Clin Endocrinol Metab       Date:  2007-06-26       Impact factor: 5.958

8.  Endogenous sex hormones and progression of carotid atherosclerosis in elderly men.

Authors:  Majon Muller; Annewieke W van den Beld; Michiel L Bots; Diederick E Grobbee; Steven W J Lamberts; Yvonne T van der Schouw
Journal:  Circulation       Date:  2004-04-19       Impact factor: 29.690

Review 9.  Ageing of the hypothalamo-pituitary-testicular axis in men.

Authors:  A Vermeulen; J M Kaufman
Journal:  Horm Res       Date:  1995

10.  Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions.

Authors:  Anthony V D'Amico; James W Denham; Juanita Crook; Ming-Hui Chen; Samuel Z Goldhaber; David S Lamb; David Joseph; Keen-Hun Tai; Shawn Malone; Charles Ludgate; Allison Steigler; Philip W Kantoff
Journal:  J Clin Oncol       Date:  2007-06-10       Impact factor: 44.544

View more
  1 in total

1.  Testosterone deficiency syndrome and cardiovascular health: Looking carefully at the evidence.

Authors:  Alvaro Morales
Journal:  Can Urol Assoc J       Date:  2014 Jan-Feb       Impact factor: 1.862

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.