Literature DB >> 24578289

A randomized trial of a prenatal genetic testing interactive computerized information aid.

Lynn M Yee1, Michael Wolf, Rebecca Mullen, Ashley R Bergeron, Stacy Cooper Bailey, Robert Levine, William A Grobman.   

Abstract

OBJECTIVE: The aim of this study was to determine whether an interactive computer program could improve patient knowledge regarding genetic screening and diagnostic concepts.
METHODS: In this randomized trial, women 6-26 weeks' gestation were assigned to standard care with provider-based counseling or to augmented counseling with an interactive computer program. The computer-based tool conveyed information about genetic testing options. Women were administered a 23-item test of content knowledge immediately and 2-4 weeks after exposure. Test scores were compared between groups at both points using T-tests.
RESULTS: A total of 150 women were randomized equally between groups. Groups were similar with regard to demographic characteristics. Women randomized to the interactive tool correctly answered a significantly greater proportion of questions than those who received standard counseling (69.4% ± 14.2% vs. 46.0% ± 15.2%, p < 0.001) on the immediate questionnaire. One hundred and twenty-three (82%) participants participated in the follow-up test. Women randomized to the tool continued to correctly answer a significantly greater proportion of questions (60.6% ± 16% vs. 49.7% ± 18.9%, p = 0.001). Education, health literacy, electronic health literacy, and other discussions with providers were not associated with a differential benefit from the educational intervention.
CONCLUSION: A patient-directed interactive computer program may help providers to convey relevant information about genetic screening and diagnostic concepts.
© 2014 John Wiley & Sons, Ltd.

Entities:  

Mesh:

Year:  2014        PMID: 24578289      PMCID: PMC4043849          DOI: 10.1002/pd.4347

Source DB:  PubMed          Journal:  Prenat Diagn        ISSN: 0197-3851            Impact factor:   3.050


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