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Literature DB >> 24576899

A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions.

Abstract

Defective asymmetric cell divisions of stem and progenitor cells are associated with tumorigenesis by a largely unknown mechanism. A signalling axis involving Snail, microRNA-146a and Numb is now shown to regulate the switch between symmetric and asymmetric cell division in colorectal cancer stem cells.

Entities: Chemical Disease Gene Species

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Year: 2014 PMID： 24576899 PMCID： PMC5453176 DOI： 10.1038/ncb2924

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

15 in total

1. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.

Authors: Hugo J Snippert; Laurens G van der Flier; Toshiro Sato; Johan H van Es; Maaike van den Born; Carla Kroon-Veenboer; Nick Barker; Allon M Klein; Jacco van Rheenen; Benjamin D Simons; Hans Clevers
Journal: Cell Date: 2010-10-01 Impact factor: 41.582

2. Optimality in the development of intestinal crypts.

Authors: Shalev Itzkovitz; Irene C Blat; Tyler Jacks; Hans Clevers; Alexander van Oudenaarden
Journal: Cell Date: 2012-02-03 Impact factor: 41.582

Review 3. Lessons from hereditary colorectal cancer.

Authors: K W Kinzler; B Vogelstein
Journal: Cell Date: 1996-10-18 Impact factor: 41.582

4. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.

Authors: Wei-Lun Hwang; Jeng-Kae Jiang; Shung-Haur Yang; Tse-Shun Huang; Hsin-Yi Lan; Hao-Wei Teng; Chih-Yung Yang; Ya-Ping Tsai; Chi-Hung Lin; Hsei-Wei Wang; Muh-Hwa Yang
Journal: Nat Cell Biol Date: 2014-03 Impact factor: 28.824

Review 5. Role of Notch signaling in colon homeostasis and carcinogenesis.

Authors: Shingo Miyamoto; Daniel W Rosenberg
Journal: Cancer Sci Date: 2011-09-06 Impact factor: 6.716

6. ID1 and ID3 regulate the self-renewal capacity of human colon cancer-initiating cells through p21.

Authors: Catherine A O'Brien; Antonija Kreso; Paul Ryan; Karin G Hermans; Lianne Gibson; Yadong Wang; Andrew Tsatsanis; Steven Gallinger; John E Dick
Journal: Cancer Cell Date: 2012-06-12 Impact factor: 31.743

7. Crypt stem cells as the cells-of-origin of intestinal cancer.

Authors: Nick Barker; Rachel A Ridgway; Johan H van Es; Marc van de Wetering; Harry Begthel; Maaike van den Born; Esther Danenberg; Alan R Clarke; Owen J Sansom; Hans Clevers
Journal: Nature Date: 2008-12-17 Impact factor: 49.962

8. A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.

Authors: Pengcheng Bu; Kai-Yuan Chen; Joyce Huan Chen; Lihua Wang; Jewell Walters; Yong Jun Shin; Julian P Goerger; Jian Sun; Mavee Witherspoon; Nikolai Rakhilin; Jiahe Li; Herman Yang; Jeff Milsom; Sang Lee; Warren Zipfel; Moonsoo M Jin; Zeynep H Gümüş; Steven M Lipkin; Xiling Shen
Journal: Cell Stem Cell Date: 2013-05-02 Impact factor: 24.633

Review 9. The miR-34 family in cancer and apoptosis.

Authors: H Hermeking
Journal: Cell Death Differ Date: 2009-05-22 Impact factor: 15.828

Review 10. Asymmetric cell division of stem and progenitor cells during homeostasis and cancer.

Authors: Sandra Gómez-López; Robin G Lerner; Claudia Petritsch
Journal: Cell Mol Life Sci Date: 2013-06-15 Impact factor: 9.261

13 in total

Review 1. Cancer stem cell division: when the rules of asymmetry are broken.

Authors: Subhas Mukherjee; Jun Kong; Daniel J Brat
Journal: Stem Cells Dev Date: 2014-12-18 Impact factor: 3.272

2. MicroRNAs and cancer: Key paradigms in molecular therapy.

Authors: Weige Tan; Bodu Liu; Shaohua Qu; Gehao Liang; Wei Luo; Chang Gong
Journal: Oncol Lett Date: 2017-12-19 Impact factor: 2.967

Review 3. NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.

Authors: Angela N Flores; Niamh McDermott; Armelle Meunier; Laure Marignol
Journal: Nat Rev Urol Date: 2014-08-19 Impact factor: 14.432

4. CCAT1 stimulation of the symmetric division of NSCLC stem cells through activation of the Wnt signalling cascade.

Authors: C Xu; G Xiao; B Zhang; M Wang; J Wang; D Liu; J Zhang; H Ren; X Sun
Journal: Gene Ther Date: 2018-01-19 Impact factor: 5.250

Review 5. Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance.

Authors: Valery Adorno-Cruz; Golam Kibria; Xia Liu; Mary Doherty; Damian J Junk; Dongyin Guan; Chris Hubert; Monica Venere; Erin Mulkearns-Hubert; Maksim Sinyuk; Alvaro Alvarado; Arnold I Caplan; Jeremy Rich; Stanton L Gerson; Justin Lathia; Huiping Liu
Journal: Cancer Res Date: 2015-01-20 Impact factor: 12.701

6. Three-Dimensional Organotypic Cultures Reshape the microRNAs Transcriptional Program in Breast Cancer Cells.

Authors: Yarely M Salinas-Vera; Jesús Valdés; Alfredo Hidalgo-Miranda; Mireya Cisneros-Villanueva; Laurence A Marchat; Stephanie I Nuñez-Olvera; Rosalio Ramos-Payán; Carlos Pérez-Plasencia; Lourdes A Arriaga-Pizano; Jessica L Prieto-Chávez; César López-Camarillo
Journal: Cancers (Basel) Date: 2022-05-19 Impact factor: 6.575