Literature DB >> 24575345

Fluorescence lifetime spectroscopy of tissue autofluorescence in normal and diseased colon measured ex vivo using a fiber-optic probe.

Sergio Coda1, Alex J Thompson2, Gordon T Kennedy3, Kim L Roche4, Lakshmana Ayaru5, Devinder S Bansi5, Gordon W Stamp6, Andrew V Thillainayagam1, Paul M W French2, Chris Dunsby7.   

Abstract

We present an ex vivo study of temporally and spectrally resolved autofluorescence in a total of 47 endoscopic excision biopsy/resection specimens from colon, using pulsed excitation laser sources operating at wavelengths of 375 nm and 435 nm. A paired analysis of normal and neoplastic (adenomatous polyp) tissue specimens obtained from the same patient yielded a significant difference in the mean spectrally averaged autofluorescence lifetime -570 ± 740 ps (p = 0.021, n = 12). We also investigated the fluorescence signature of non-neoplastic polyps (n = 6) and inflammatory bowel disease (n = 4) compared to normal tissue in a small number of specimens.

Entities:  

Keywords:  (120.3890) Medical optics instrumentation; (170.2680) Gastrointestinal; (170.3650) Lifetime-based sensing; (300.6500) Spectroscopy, time-resolved; (300.6540) Spectroscopy, ultraviolet; (300.6550) Spectroscopy, visible

Year:  2014        PMID： 24575345      PMCID： PMC3920881          DOI： 10.1364/BOE.5.000515

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  56 in total

1.  Endoscopic tissue characterization by frequency-domain fluorescence lifetime imaging (FD-FLIM).

Authors:  J Mizeret; G Wagnières; T Stepinac; H Van Den Bergh
Journal:  Lasers Med Sci       Date:  1997-10       Impact factor: 3.161

2.  Polarized near-infrared autofluorescence imaging combined with near-infrared diffuse reflectance imaging for improving colonic cancer detection.

Authors:  Xiaozhuo Shao; Wei Zheng; Zhiwei Huang
Journal:  Opt Express       Date:  2010-11-08       Impact factor: 3.894

3.  In vivo measurements of diffuse reflectance and time-resolved autofluorescence emission spectra of basal cell carcinomas.

Authors:  Alex J Thompson; Sergio Coda; Mikkel Brydegaard Sørensen; Gordon Kennedy; Rakesh Patalay; Ulrika Waitong-Brämming; Pieter A A De Beule; Mark A A Neil; Stefan Andersson-Engels; Niels Bendsøe; Paul M W French; Katarina Svanberg; Chris Dunsby
Journal:  J Biophotonics       Date:  2012-02-06       Impact factor: 3.207

Review 4.  Fluorescence lifetime techniques in medical applications.

Authors:  Laura Marcu
Journal:  Ann Biomed Eng       Date:  2012-01-25       Impact factor: 3.934

5.  Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropy.

Authors:  Harshad D Vishwasrao; Ahmed A Heikal; Karl A Kasischke; Watt W Webb
Journal:  J Biol Chem       Date:  2005-04-29       Impact factor: 5.157

6.  In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia.

Authors:  Melissa C Skala; Kristin M Riching; Annette Gendron-Fitzpatrick; Jens Eickhoff; Kevin W Eliceiri; John G White; Nirmala Ramanujam
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-27       Impact factor: 11.205

7.  Light-induced autofluorescence spectroscopy for the endoscopic detection of esophageal cancer.

Authors:  B Mayinger; P Horner; M Jordan; C Gerlach; T Horbach; W Hohenberger; E G Hahn
Journal:  Gastrointest Endosc       Date:  2001-08       Impact factor: 9.427

8.  Ultraviolet laser-induced fluorescence of colonic polyps.

Authors:  K T Schomacker; J K Frisoli; C C Compton; T J Flotte; J M Richter; T F Deutsch; N S Nishioka
Journal:  Gastroenterology       Date:  1992-04       Impact factor: 22.682

9.  Gastrointestinal tissue diagnosis by laser-induced fluorescence spectroscopy at endoscopy.

Authors:  R M Cothren; R Richards-Kortum; M V Sivak; M Fitzmaurice; R P Rava; G A Boyce; M Doxtader; R Blackman; T B Ivanc; G B Hayes
Journal:  Gastrointest Endosc       Date:  1990 Mar-Apr       Impact factor: 9.427

10.  The distribution of collagen types I, III, and IV in normal and malignant colorectal mucosa.

Authors:  M Hilska; Y Collan; J Peltonen; R Gullichsen; H Paajanen; M Laato
Journal:  Eur J Surg       Date:  1998-06
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  22 in total

1.  Two-Photon Lifetime Imaging of Voltage Indicating Proteins as a Probe of Absolute Membrane Voltage.

Authors:  Daan Brinks; Aaron J Klein; Adam E Cohen
Journal:  Biophys J       Date:  2015-09-01       Impact factor: 4.033

2.  Electrocautery effects on fluorescence lifetime measurements: An in vivo study in the oral cavity.

Authors:  João L Lagarto; Jennifer E Phipps; Leta Faller; Dinglong Ma; Jakob Unger; Julien Bec; Stephen Griffey; Jonathan Sorger; D Gregory Farwell; Laura Marcu
Journal:  J Photochem Photobiol B       Date:  2018-05-26       Impact factor: 6.252

3.  Optically sectioned wide-field fluorescence lifetime imaging microscopy enabled by structured illumination.

Authors:  Taylor Hinsdale; Cory Olsovsky; Jose J Rico-Jimenez; Kristen C Maitland; Javier A Jo; Bilal H Malik
Journal:  Biomed Opt Express       Date:  2017-02-08       Impact factor: 3.732

4.  Introduction: feature issue on optical molecular probes, imaging, and drug delivery.

Authors:  Paul Campagnola; Paul M W French; Irene Georgakoudi; Mary-Ann Mycek
Journal:  Biomed Opt Express       Date:  2014-01-29       Impact factor: 3.732

Review 5.  Molecular probes for fluorescence lifetime imaging.

Authors:  Pinaki Sarder; Dolonchampa Maji; Samuel Achilefu
Journal:  Bioconjug Chem       Date:  2015-05-22       Impact factor: 4.774

6.  Real-Time Visualization of Tissue Surface Biochemical Features Derived From Fluorescence Lifetime Measurements.

Authors:  Dimitris Gorpas; Dinglong Ma; Julien Bec; Diego R Yankelevich; Laura Marcu
Journal:  IEEE Trans Med Imaging       Date:  2016-02-15       Impact factor: 10.048

7.  Time-resolved fluorescence spectroscopy for clinical diagnosis of actinic cheilitis.

Authors:  Alessandro Cosci; Marcelo Saito Nogueira; Sebastião Pratavieira; Ademar Takahama; Rebeca de Souza Azevedo; Cristina Kurachi
Journal:  Biomed Opt Express       Date:  2016-09-21       Impact factor: 3.732

8.  Advanced Fluorescence Microscopy Methods to Study Dynamics of Fluorescent Proteins In Vivo.

Authors:  Marcela Díaz; Leonel Malacrida
Journal:  Methods Mol Biol       Date:  2023

9.  Application of time-resolved autofluorescence to label-free in vivo optical mapping of changes in tissue matrix and metabolism associated with myocardial infarction and heart failure.

Authors:  João Lagarto; Benjamin T Dyer; Clifford Talbot; Markus B Sikkel; Nicholas S Peters; Paul M W French; Alexander R Lyon; Chris Dunsby
Journal:  Biomed Opt Express       Date:  2015-01-07       Impact factor: 3.732

10.  Multispectral fluorescence lifetime imaging device with a silicon avalanche photodetector.

Authors:  Xiangnan Zhou; Julien Bec; Diego Yankelevich; Laura Marcu
Journal:  Opt Express       Date:  2021-06-21       Impact factor: 3.833
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