Literature DB >> 24574174

Supramolecular nanofibrils inhibit cancer progression in vitro and in vivo.

Yi Kuang1, Xuewen Du, Jie Zhou, Bing Xu.   

Abstract

Self-assembly of small peptide derivatives affords supramolecular nanofibrils that possess characteristic features of amyloid oligomers. Acting as de novo amyloid oligomers, the nanofibrils effectively inhibit the tumor progression both in vitro and in vivo, which demonstrates a new type of anticancer approach and may provide new insights for inverse comorbidity between cancer and neurodegenerative diseases.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  anticancer; de novo amyloid; inverse comorbidity; nanofibrils; supramolecular

Mesh：

Substances：

Year:  2014        PMID： 24574174      PMCID： PMC4134730          DOI： 10.1002/adhm.201300645

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  21 in total

1.  Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.

Authors:  Rakez Kayed; Elizabeth Head; Jennifer L Thompson; Theresa M McIntire; Saskia C Milton; Carl W Cotman; Charles G Glabe
Journal:  Science       Date:  2003-04-18       Impact factor: 47.728

Review 2.  Protein folding and misfolding.

Authors:  Christopher M Dobson
Journal:  Nature       Date:  2003-12-18       Impact factor: 49.962

3.  Using circular dichroism spectra to estimate protein secondary structure.

Authors:  Norma J Greenfield
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

Review 4.  No paradox, no progress: inverse cancer comorbidity in people with other complex diseases.

Authors:  Rafael Tabarés-Seisdedos; Nancy Dumont; Anaïs Baudot; Jose M Valderas; Joan Climent; Alfonso Valencia; Benedicto Crespo-Facorro; Eduard Vieta; Manuel Gómez-Beneyto; Salvador Martínez; John L Rubenstein
Journal:  Lancet Oncol       Date:  2011-04-15       Impact factor: 41.316

5.  Amyloid toxicity is independent of polypeptide sequence, length and chirality.

Authors:  M Teresa Pastor; Nico Kümmerer; Vanessa Schubert; Alexandra Esteras-Chopo; Carlos G Dotti; Manuela López de la Paz; Luis Serrano
Journal:  J Mol Biol       Date:  2007-08-21       Impact factor: 5.469

6.  Annual Report to the Nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity.

Authors:  Christie Eheman; S Jane Henley; Rachel Ballard-Barbash; Eric J Jacobs; Maria J Schymura; Anne-Michelle Noone; Liping Pan; Robert N Anderson; Janet E Fulton; Betsy A Kohler; Ahmedin Jemal; Elizabeth Ward; Marcus Plescia; Lynn A G Ries; Brenda K Edwards
Journal:  Cancer       Date:  2012-03-28       Impact factor: 6.860

7.  Disruption of the dynamics of microtubules and selective inhibition of glioblastoma cells by nanofibers of small hydrophobic molecules.

Authors:  Yi Kuang; Bing Xu
Journal:  Angew Chem Int Ed Engl       Date:  2013-05-17       Impact factor: 15.336

8.  Purification and characterization of brain clusterin.

Authors:  T Oda; G M Pasinetti; H H Osterburg; C Anderson; S A Johnson; C E Finch
Journal:  Biochem Biophys Res Commun       Date:  1994-11-15       Impact factor: 3.575

9.  Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases.

Authors:  Monica Bucciantini; Elisa Giannoni; Fabrizio Chiti; Fabiana Baroni; Lucia Formigli; Jesús Zurdo; Niccolò Taddei; Giampietro Ramponi; Christopher M Dobson; Massimo Stefani
Journal:  Nature       Date:  2002-04-04       Impact factor: 49.962

10.  Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines.

Authors:  J E Liebmann; J A Cook; C Lipschultz; D Teague; J Fisher; J B Mitchell
Journal:  Br J Cancer       Date:  1993-12       Impact factor: 7.640
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  15 in total

Review 1.  Supramolecular biomaterials.

Authors:  Matthew J Webber; Eric A Appel; E W Meijer; Robert Langer
Journal:  Nat Mater       Date:  2016-01       Impact factor: 43.841

Review 2.  Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials.

Authors:  Xuewen Du; Jie Zhou; Junfeng Shi; Bing Xu
Journal:  Chem Rev       Date:  2015-12-08       Impact factor: 60.622

3.  Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics.

Authors:  Yi Kuang; Marcus J C Long; Jie Zhou; Junfeng Shi; Yuan Gao; Chen Xu; Lizbeth Hedstrom; Bing Xu
Journal:  J Biol Chem       Date:  2014-08-25       Impact factor: 5.157

Review 4.  Supramolecular biofunctional materials.

Authors:  Jie Zhou; Jie Li; Xuewen Du; Bing Xu
Journal:  Biomaterials       Date:  2017-03-12       Impact factor: 12.479

Review 5.  D-amino acid-containing supramolecular nanofibers for potential cancer therapeutics.

Authors:  Huaimin Wang; Zhaoqianqi Feng; Bing Xu
Journal:  Adv Drug Deliv Rev       Date:  2016-04-19       Impact factor: 15.470

6.  Nanoscale Assemblies of Small Molecules Control the Fate of Cells.

Authors:  Junfeng Shi; Bing Xu
Journal:  Nano Today       Date:  2015-10-20       Impact factor: 20.722

7.  Prion-like nanofibrils of small molecules (PriSM): A new frontier at the intersection of supramolecular chemistry and cell biology.

Authors:  Jie Zhou; Xuewen Du; Bing Xu
Journal:  Prion       Date:  2015       Impact factor: 3.931

Review 8.  Enzymatic noncovalent synthesis of peptide assemblies generates multimolecular crowding in cells for biomedical applications.

Authors:  Meihui Yi; Weiyi Tan; Jiaqi Guo; Bing Xu
Journal:  Chem Commun (Camb)       Date:  2021-12-03       Impact factor: 6.222

Review 9.  Self-assembling prodrugs.

Authors:  Andrew G Cheetham; Rami W Chakroun; Wang Ma; Honggang Cui
Journal:  Chem Soc Rev       Date:  2017-10-30       Impact factor: 54.564

Review 10.  Recent Progress in the Design and Medical Application of In Situ Self-Assembled Polypeptide Materials.

Authors:  Tian-Tian Wang; Yi-Yi Xia; Jian-Qing Gao; Dong-Hang Xu; Min Han
Journal:  Pharmaceutics       Date:  2021-05-19       Impact factor: 6.321
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