Literature DB >> 24573866

Partial portacaval shunt with H-grafts to treat portal hypertension.

Geliang Xu1, Hejie Hu, Jiansheng Li, Shugao Yang, Zhongpei Chai, Rongnan Xu.   

Abstract

Partial portosystemic shunts have been popularized because of a reported low rate of mortality and morbidity (especially encephalopathy, liver failure and occlusion). The results of partial portacaval shunts [small-diameter expanded polytetrafluoroethylene (ePTFE) H-graft portacaval shunt] were retrospectively reviewed to evaluate the clinical efficacy in the treatment of portal hypertension. Forty-three patients with portal hypertension were treated by small-diameter H-graft of ePTFE portacaval shunt from May 1995 to April 2006. Thirty-three had externally ringed grafts and ten had non-ringed ones. Ten had grafts of 10 mm in diameter and 33 had grafts of 8 mm. The left gastric artery and coronary vein were ligated in all the cases. Six had pericardial devascularization and splenectomy was performed in 42. An average decrease of free portal pressure (FPP) from (33.24 ± 4.78) cmH2O before shunting and (13.65 ± 5.65) cmH2O after shunting was observed. The portal blood flow was reduced by one-third of that before shunt. Thirty-eight patients survived and no upper gastro-intestinal rebleeding occurred in the follow-up period (50.5 months in average). Two were out of contact. Color Doppler ultrasonography and/or portography revealed the shunts were patent in 38 cases and were occluded in three cases (3/41, 7.3%). Encephalopathy developed in five cases (5/41, 12.2%). Partial (small-diameter ePTFE H-graft) portacaval shunting can reduce the portal pressure effectively. Majority of the hepatic flow from the portal vein can be maintained adequately. The shunts with reinforced grafts can keep a higher rate of patency. The morbidity of encephalopathy was lower than those with total shunt. The partial portacaval shunt is effective in preventing recurrent variceal bleeding.

Entities:  

Year:  2007        PMID: 24573866     DOI: 10.1007/s11684-007-0053-z

Source DB:  PubMed          Journal:  Front Med China        ISSN: 1673-7342


  5 in total

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Authors:  J M Henderson; D S Barnes; M A Geisinger
Journal:  Curr Probl Surg       Date:  1998-05       Impact factor: 1.909

2.  [Portacaval shunt with H-grafts of small diameter in treating cirrhotic patients with portal hypertension].

Authors:  X Leng; J Zhu; R Du
Journal:  Zhonghua Wai Ke Za Zhi       Date:  1998-06

3.  Small-diameter H-graft portacaval shunt reduces portal flow yet maintains effective hepatic blood flow.

Authors:  E E Zervos; S E Goode; A S Rosemurgy
Journal:  Am Surg       Date:  1998-01       Impact factor: 0.688

4.  Small diameter H-graft porta-caval shunt performed at different stages of liver disease.

Authors:  Giacomo Batignani; Francesco Vizzutti; Luigi Rega; Michele Zuckermann; Geri Fratini; Massimo Pinzani; Francesco Tonelli
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2004-11

5.  A systematic appraisal of portacaval H-graft diameters. Clinical and hemodynamic perspectives.

Authors:  I J Sarfeh; E B Rypins; G R Mason
Journal:  Ann Surg       Date:  1986-10       Impact factor: 12.969

  5 in total

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