Literature DB >> 24572726

Swallowing impairment and pulmonary dysfunction in Parkinson's disease: the silent threats.

Larissa Monteiro1, Adelmir Souza-Machado2, Patrícia Pinho3, Marília Sampaio3, Ana Caline Nóbrega3, Ailton Melo3.   

Abstract

INTRODUCTION: Swallowing disorders and respiratory impairment are frequent in Parkinson's disease (PD) patients, and aspiration pneumonia remains the leading cause of death among these subjects.
OBJECTIVE: The objective of this study was to investigate whether there is an association between pulmonary impairment and swallowing dysfunction in PD patients.
METHODS: A cross-sectional study with a comparison group was conducted with PD patients. Subjects were submitted to demographic questionnaires and underwent spirometric and videofluorographic assessments. Significance level was considered at 95% (p<0.05).
RESULTS: Among 35 PD patients, 40% presented with swallowing complaints. However, 22% of the clinically asymptomatic patients presented airway food penetration when submitted to videofluoroscopy. In 20% of PD patients material entered the airways and there was contact with the vocal folds in 7%. However, there was an efficient cleaning with residue deglutition in almost all patients. No penetration/aspiration was detected among the controls. Respiratory parameters were below the normal predicted values in PD patients when compared to the healthy controls.
CONCLUSION: These data suggest an association between pulmonary dysfunction and swallowing impairment in PD patients; even in patients without swallowing complaints, impaired pulmonary function can be detected.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Deglutition; Dysphagia; Parkinson's disease; Pulmonary function; Respiratory dysfunction; Swallowing

Mesh:

Year:  2014        PMID: 24572726     DOI: 10.1016/j.jns.2014.02.004

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  16 in total

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10.  Are Upper-Body Axial Symptoms a Feature of Early Parkinson's Disease?

Authors:  Caroline Moreau; David Devos; Guillaume Baille; Arnaud Delval; Céline Tard; Thierry Perez; Nicolas Danel-Buhl; David Seguy; Julien Labreuche; Alain Duhamel; Marie Delliaux; Kathy Dujardin; Luc Defebvre
Journal:  PLoS One       Date:  2016-09-21       Impact factor: 3.240

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