Literature DB >> 24572114

[Interleukin-7, a new immunoadjuvant for the treatment of septic shock].

Guillaume Monneret1, Astrid Villars-Méchin2, Julie Demaret1, Anne-Perrine Foray2, Fabienne Venet1.   

Abstract

Sepsis-induced immunosuppression is a new paradigm in sepsis pathophysiology. This up-to-date review integrates recent facts in the field. It focuses on immune dysfunctions described so far in septic patients (especially regarding T lymphocytes), on the mechanisms sustaining this immune failure, on the monitoring of the pro-/anti-inflammatory balance rapidly changing over time and on new promising therapeutic avenues emerging from those recent findings. Of them, the case of interleukin-7 is more specifically envisaged.
© 2014 médecine/sciences – Inserm.

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Year:  2014        PMID: 24572114     DOI: 10.1051/medsci/20143002013

Source DB:  PubMed          Journal:  Med Sci (Paris)        ISSN: 0767-0974            Impact factor:   0.818


  1 in total

1.  The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.

Authors:  Binyu Luo; Kang Chen; Qi Feng; Weidong Xiao; Dan Ma; Hua Yang; Chaojun Zhang
Journal:  Int J Mol Med       Date:  2018-02-09       Impact factor: 4.101

  1 in total

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