Literature DB >> 24569937

Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis.

S Peker1, S Mete, Y Gokdemir, B Karadag, B Kargul.   

Abstract

AIM: To investigate dental caries and molar incisor hypomineralisation (MIH)-related factors such as treatment, diet, brushing and salivary factors in children with cystic fibrosis (CF) compared with healthy peers. STUDY
DESIGN: A cohort study was performed.
METHODS: This study was performed on 30 CF children comprising patients at the Faculty of Medicine and 30 control children recruited from the Dental School. Salivary factors, dental caries, MIH, daily diet, brushing habits were analysed. Statistical analysis was calculated by SPSS for Windows.
RESULTS: Decay missing filled teeth (DMF-T) score was 4.6 ± 4.0 in CF and 7.7 ± 2.7 in control (p = 0.001). 43% of CF children with MIH were found to use antibiotics, but no significant difference in the caries experience was found with antibiotic usage (p > 0.05). DMF-T of CF adolescents (23%) who use Tobramycin was 7 ± 3.5. DMF-T of CF children (20%) who take other antibiotics was 2.5 ± 3.5, but no statistical difference was found (p = 0.054). Saliva pH, salivary flow rate, and buffering capacity were not found statistically significant (p > 0.05). STATISTICS: Percentage arithmetic mean value, standard deviation, independent sample t test, Fisher's exact test, Chi-square test and Mann-Whitney U test were used, while a p value of <0.05 was considered statistically significant.
CONCLUSIONS: Medication and diet could be considered as a risk factor for dental caries and factors such as salivary pH, good oral hygiene could play a protective role for oral health CF children. MIH frequency and lower caries experience seen in CF children could be due to salivary factors or pharmacological treatment they take. The multidisciplinary approach team would be advantageous in the management of children with CF and oral health should be under control during early years of life by paediatric dentists.

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Year:  2014        PMID: 24569937     DOI: 10.1007/s40368-014-0112-5

Source DB:  PubMed          Journal:  Eur Arch Paediatr Dent        ISSN: 1818-6300


  37 in total

1.  Salivary electrolyte concentrations are associated with cystic fibrosis transmembrane regulator genotypes.

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Authors:  Robert Bals; Dominique Hubert; Burkhard Tümmler
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Journal:  Biol Trace Elem Res       Date:  2001-10       Impact factor: 3.738

5.  An in vivo investigation of salivary properties, enamel hypomineralisation, and carious lesion severity in a group of Iraqi schoolchildren.

Authors:  Aghareed Ghanim; Rodrigo Mariño; Michael Morgan; Denise Bailey; David Manton
Journal:  Int J Paediatr Dent       Date:  2012-01-18       Impact factor: 3.455

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Authors:  J K Aps; G O Van Maele; L C Martens
Journal:  Eur J Paediatr Dent       Date:  2002-12       Impact factor: 2.231

8.  Presence of developmental defects of enamel in cystic fibrosis patients.

Authors:  Tatiana Degani Paes Leme Azevedo; Gilvania Coutinho Silva Feijó; Ana Cristina Barreto Bezerra
Journal:  J Dent Child (Chic)       Date:  2006 Sep-Dec

9.  Molar incisor hypomineralization: review and prevalence data from the study of primary school children in Kaunas/Lithuania.

Authors:  L Jasulaityte; J S Veerkamp; K L Weerheijm
Journal:  Eur Arch Paediatr Dent       Date:  2007-06

Review 10.  New antimicrobial strategies in cystic fibrosis.

Authors:  Mireille van Westreenen; Harm A W M Tiddens
Journal:  Paediatr Drugs       Date:  2010-12-01       Impact factor: 3.022

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  6 in total

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Authors:  Rodrigo S Lacruz; Stefan Habelitz; J Timothy Wright; Michael L Paine
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2.  Unstimulated Saliva-Related Caries Risk Factors in Individuals with Cystic Fibrosis: A Cross-Sectional Analysis of Unstimulated Salivary Flow, pH, and Buffering Capacity.

Authors:  Alaa A Alkhateeb; Lloyd A Mancl; Richard B Presland; Marilynn L Rothen; Donald L Chi
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3.  Oral Hygiene and Periodontal Treatment Needs in Adult Patients with Cystic Fibrosis (CF).

Authors:  Tomasz Hildebrandt; Elżbieta Świętochowska; Agata Trzcionka; Anna Zawilska; Henryk Mazurek; Dagmara Mączkowiak; Mansur Rahnama; Marta Tanasiewicz
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4.  Toothbrushes may convey bacteria to the cystic fibrosis lower airways.

Authors:  Rebeca Passarelli Mantovani; Angela Sandri; Marzia Boaretti; Alessandra Grilli; Sonia Volpi; Paola Melotti; Gloria Burlacchini; Maria M Lleò; Caterina Signoretto
Journal:  J Oral Microbiol       Date:  2019-08-07       Impact factor: 5.474

5.  Salivary Biomarkers and Oral Microbial Load in Relation to the Dental Status of Adults with Cystic Fibrosis.

Authors:  Tamara Pawlaczyk-Kamieńska; Maria Borysewicz-Lewicka; Halina Batura-Gabryel
Journal:  Microorganisms       Date:  2019-12-13

6.  An update of the aetiological factors involved in molar incisor hypomineralisation (MIH): a systematic review and meta-analysis.

Authors:  E Garot; P Rouas; C Somani; G D Taylor; F Wong; N A Lygidakis
Journal:  Eur Arch Paediatr Dent       Date:  2021-06-24
  6 in total

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