| Literature DB >> 24567954 |
Laura G Carrascosa1, Abu Ali Ibn Sina, Ramkumar Palanisamy, Borja Sepulveda, Marinus A Otte, Sakandar Rauf, Muhamad J A Shiddiky, Matt Trau.
Abstract
DNA methylation has the potential to be a clinically important biomarker in cancer. This communication reports a real-time and label-free biosensing strategy for DNA methylation detection in the cancer cell line. This has been achieved by using surface plasmon resonance biosensing combined with the highly specific molecular inversion probe based amplification method, which requires only 50 ng of bisulfite treated genomic DNA.Entities:
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Year: 2014 PMID: 24567954 DOI: 10.1039/c3cc49607d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222