Literature DB >> 24567804

Rationale, design and baseline patient characteristics of the optimal type 2 diabetes management including benchmarking and standard treatment study in Greece.

Michael S Kostapanos1, Vasilis Tsimihodimos1, Moses S Elisaf1, Emmanouil Tzouvelekis1, Nikos Nikas1.   

Abstract

AIM: To describe baseline data of the optimal type 2 diabetes management including benchmarking and standard treatment (OPTIMISE) study in Greece.
METHODS: "Benchmarking" is the process of receiving feedback comparing one's performance with that of others. The OPTIMISE (NCT00681850) study is a multinational, multicenter study assessing, at a primary care level, whether using "benchmarking" can help to improve the quality of patient care, compared with a set of guideline-based reference values ("non-benchmarking"). In the Greek region, 797 outpatients (457 men, mean age 63.8 years) with type 2 diabetes were enrolled by 84 office-based physicians. Baseline characteristics of this population are presented.
RESULTS: Hypertension was the most prevalent concomitant disorder (77.3%) and coronary heart disease was the most frequent macrovascular complication of diabetes (23.8%). Most patients were overweight or obese (body mass index 29.6 ± 5 kg/m(2)), exhibiting mostly abdominal obesity (waist circumference 102.6 ± 13.6 cm). Biguanides were the most prevalent prescribed drugs for the management of diabetes (70.1% of all prescriptions), whereas statins (93.5% of all prescriptions) and angiotensin receptor blockers (55.8% of all prescriptions) were the most prevalent prescribed drugs for hyperlipidemia and hypertension, respectively. Only 37.4% of patients were on aspirin. Despite treatment, pre-defined targets for fasting plasma glucose (< 110 mg/dL), glycated hemoglobin (< 7%), systolic blood pressure (< 130 mmHg and < 125 mmHg for patients with proteinuria) and low density lipoprotein cholesterol levels (< 100 mg/dL and < 70 mg/dL for patients with coronary heart disease) were reached in a relatively small proportion of patients (29%, 53%, 27% and 31%, respectively). In a Greek population with type 2 diabetes, the control of glycemia or concomitant disorders which increase cardiovascular risk remains poor.
CONCLUSION: Despite relevant treatment, there is a poor control of diabetes, hypertension and hyperlipidemia in Greek outpatients with type 2 diabetes.

Entities:  

Keywords:  Benchmarking; Blood pressure; Diabetes; Dyslipidemia; Glycemic control; Treatment target

Year:  2014        PMID: 24567804      PMCID: PMC3932430          DOI: 10.4239/wjd.v5.i1.76

Source DB:  PubMed          Journal:  World J Diabetes        ISSN: 1948-9358


  23 in total

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Journal:  Eur Heart J       Date:  2007-01       Impact factor: 29.983

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Journal:  BMJ       Date:  2001-09-15

5.  Optimal type 2 diabetes mellitus management: the randomised controlled OPTIMISE benchmarking study: baseline results from six European countries.

Authors:  Michel P Hermans; Carlos Brotons; Moses Elisaf; Georges Michel; Erik Muls; Frank Nobels
Journal:  Eur J Prev Cardiol       Date:  2012-05-17       Impact factor: 7.804

6.  High prevalence and suboptimal treatment of risk factors in Greek coronary patients.

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Journal:  Acta Cardiol       Date:  2001-02       Impact factor: 1.718

7.  Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries; principal results from EUROASPIRE II Euro Heart Survey Programme.

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Journal:  Eur Heart J       Date:  2001-04       Impact factor: 29.983

8.  Prevalence, awareness, treatment, and control of hypertension in Greece: the Didima study.

Authors:  G S Stergiou; G C Thomopoulou; I I Skeva; T D Mountokalakis
Journal:  Am J Hypertens       Date:  1999-10       Impact factor: 2.689

9.  Evidence for an increase in the prevalence of known diabetes in a sample of an urban population in Greece.

Authors:  N Katsilambros; K Aliferis; C Darviri; P Tsapogas; Z Alexiou; N Tritos; M Arvanitis
Journal:  Diabet Med       Date:  1993 Jan-Feb       Impact factor: 4.359

10.  Hypertriglyceridaemic waist phenotype criteria and prevalent metabolic triad in women.

Authors:  Irene F Gazi; Haralampos J Milionis; Theodosios D Filippatos; Vasilis Tsimihodimos; Michael S Kostapanos; Michael Doumas; Alexandros D Tselepis; Moses Elisaf
Journal:  Diabetes Metab Res Rev       Date:  2008 Mar-Apr       Impact factor: 4.876

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  1 in total

1.  Effects of benchmarking on the quality of type 2 diabetes care: results of the OPTIMISE (Optimal Type 2 Diabetes Management Including Benchmarking and Standard Treatment) study in Greece.

Authors:  Vasilis Tsimihodimos; Michael S Kostapanos; Alexandros Moulis; Nikos Nikas; Moses S Elisaf
Journal:  Ther Adv Endocrinol Metab       Date:  2015-10       Impact factor: 3.565

  1 in total

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