Literature DB >> 24566880

NAFLD. Metabolic make-up of NASH: from fat and sugar to amino acids.

Silvia Sookoian1, Carlos J Pirola2.   

Abstract

NAFLD is regarded unquestionably as one of the components of the metabolic syndrome. Hence, metabolic perturbations occurring in the fatty liver become a systemic metabolic derangement. The phenotypic switching from fatty liver to NASH entails a reprogramming of liver metabolism to fit a stressful metabolic environment.

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Year:  2014        PMID： 24566880     DOI： 10.1038/nrgastro.2014.25

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


  18 in total

1.  Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation.

Authors:  Silvia Sookoian; Carlos J Pirola
Journal:  Hepatobiliary Surg Nutr       Date:  2017-04       Impact factor: 7.293

Review 2.  The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease.

Authors:  Yue Zhao; Tian-Yu Wu; Meng-Fei Zhao; Chao-Jun Li
Journal:  J Biol Chem       Date:  2020-03-05       Impact factor: 5.157

Review 3.  Liver enzymes, metabolomics and genome-wide association studies: from systems biology to the personalized medicine.

Authors:  Silvia Sookoian; Carlos J Pirola
Journal:  World J Gastroenterol       Date:  2015-01-21       Impact factor: 5.742

4.  Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.

Authors:  Christine Bernsmeier; Michael T Dill; Angela Provenzano; Zuzanna Makowska; Ilona Krol; Giovanna Muscogiuri; David Semela; Luigi Tornillo; Fabio Marra; Markus H Heim; François H T Duong
Journal:  Lab Invest       Date:  2016-07-18       Impact factor: 5.662

5.  Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome.

Authors:  Oren Rom; Yuhao Liu; Zhipeng Liu; Ying Zhao; Jianfeng Wu; Alia Ghrayeb; Luis Villacorta; Yanbo Fan; Lin Chang; Lu Wang; Cai Liu; Dongshan Yang; Jun Song; Jason C Rech; Yanhong Guo; Huilun Wang; Guizhen Zhao; Wenying Liang; Yui Koike; Haocheng Lu; Tomonari Koike; Tony Hayek; Subramaniam Pennathur; Chuanwu Xi; Bo Wen; Duxin Sun; Minerva T Garcia-Barrio; Michael Aviram; Eyal Gottlieb; Inbal Mor; Wanqing Liu; Jifeng Zhang; Y Eugene Chen
Journal:  Sci Transl Med       Date:  2020-12-02       Impact factor: 17.956

6.  Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach.

Authors:  Ran Jin; Rob McConnell; Cioffi Catherine; Shujing Xu; Douglas I Walker; Nikos Stratakis; Dean P Jones; Gary W Miller; Cheng Peng; David V Conti; Miriam B Vos; Leda Chatzi
Journal:  Environ Int       Date:  2019-11-16       Impact factor: 13.352

Review 7.  Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity.

Authors:  Carlos J Pirola; Silvia Sookoian
Journal:  World J Gastroenterol       Date:  2018-04-21       Impact factor: 5.742

8.  Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH).

Authors:  Silvia Sookoian; Gustavo O Castaño; Romina Scian; Julio San Martino; Carlos J Pirola
Journal:  Sci Rep       Date:  2016-03-03       Impact factor: 4.379

9.  Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid.

Authors:  Wonbeak Yoo; Donjeta Gjuka; Heather L Stevenson; Xiaoling Song; Hong Shen; Suk Young Yoo; Jing Wang; Michael Fallon; George N Ioannou; Stephen A Harrison; Laura Beretta
Journal:  PLoS One       Date:  2017-12-15       Impact factor: 3.240

10.  Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children.

Authors:  Nikos Stratakis; David V Conti; Ran Jin; Katerina Margetaki; Damaskini Valvi; Alexandros P Siskos; Léa Maitre; Erika Garcia; Nerea Varo; Yinqi Zhao; Theano Roumeliotaki; Marina Vafeiadi; Jose Urquiza; Silvia Fernández-Barrés; Barbara Heude; Xavier Basagana; Maribel Casas; Serena Fossati; Regina Gražulevičienė; Sandra Andrušaitytė; Karan Uppal; Rosemary R C McEachan; Eleni Papadopoulou; Oliver Robinson; Line Småstuen Haug; John Wright; Miriam B Vos; Hector C Keun; Martine Vrijheid; Kiros T Berhane; Rob McConnell; Lida Chatzi
Journal:  Hepatology       Date:  2020-10-19       Impact factor: 17.425
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