Literature DB >> 24566565

Telogen effluvium revisited.

A Rebora1.   

Abstract

Telogen effluvium (TE) is heterogeneous disorder. It can be classified into three main categories: the premature teloptosis, the collective teloptosis and the premature entry into telogen. The last category can be divided in three types: the drug induced TE, TE due to dietary deficiencies and the "autoimmune" TE. Despite this heterogeneity, the large majority of TE that arrive at the dermatologist's observation pertain to the autoimmune type, featuring a standard presentation. The typical patient is a woman claiming to have always had a "full head of hair" and reporting her hair to come out suddenly "by the handful". Usually, she is accurate about the date of onset of her shedding. She is in good health, without signs of anorexia nor nutrient deficiencies. She admits to having been in an anxious state for some months, and felt, occasionally or not, a painful or burning sensation at the scalp (trichodynia). Usually, the course of the disorder is chronic but intermittent, with apparent remissions being irregularly intermitted by relapses. The shed hairs do not exhibit telogen roots, but mostly exogen ones. This distinct entity, shares some analogies with alopecia areata, including the triggering role of emotional stress, trichodynia and the frequent association with Hashimoto's thyroiditis. Methods to assess its severity and to monitor treatment are described. In the absence of a documented etiopathogenesis, no treatment can be endorsed, but a course of topical corticosteroids could be tried.

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Year:  2014        PMID: 24566565

Source DB:  PubMed          Journal:  G Ital Dermatol Venereol        ISSN: 0392-0488            Impact factor:   2.011


  2 in total

Review 1.  Drug discovery for alopecia: gone today, hair tomorrow.

Authors:  Zenildo Santos; Pinar Avci; Michael R Hamblin
Journal:  Expert Opin Drug Discov       Date:  2015-02-09       Impact factor: 6.098

2.  t-Flavanone Improves the Male Pattern of Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study.

Authors:  Azumi Nagasawa; Etsuji Wakisaka; Hideshi Kidena; Tomoko Nomura; Mitsuyuki Hotta; Hiroyuki Taguchi; Shigeru Moriwaki
Journal:  Dermatol Ther (Heidelb)       Date:  2016-02-20
  2 in total

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