Literature DB >> 24566411

18F-DOPA, a clinically available PET tracer to study brain inflammation?

Quentin Sala1, Philippe Metellus, David Taieb, Elsa Kaphan, Dominique Figarella-Branger, Eric Guedj.   

Abstract

We report 2 cases of suspected low-grade glioma with positive 18F-fluorodihydroxyphenylalanine (18F-FDOPA) PET scan, and histological diagnosis of brain inflammation corresponding to an acute disseminated encephalomyelitis (ADEM) and to a neurosarcoidosis. It has been shown that this amino-acid PET radiotracer serves to evaluate tumoral proliferation related to the metabolism of L-amino-acid transporters, and that inflammation may also contribute to the tumoral uptake. This report suggests it may serve to study brain inflammation.

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Year:  2014        PMID： 24566411     DOI： 10.1097/RLU.0000000000000383

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  9 in total

1.  Diagnostic and prognostic value of 18F-DOPA PET and 1H-MR spectroscopy in pediatric supratentorial infiltrative gliomas: a comparative study.

Authors:  Giovanni Morana; Arnoldo Piccardo; Matteo Puntoni; Paolo Nozza; Armando Cama; Alessandro Raso; Samantha Mascelli; Michela Massollo; Claudia Milanaccio; Maria Luisa Garrè; Andrea Rossi
Journal:  Neuro Oncol       Date:  2015-09-23       Impact factor: 12.300

2.  [18F] FDOPA standardized uptake values of brain tumors are not exclusively dependent on LAT1 expression.

Authors:  Bérengère Dadone-Montaudié; Damien Ambrosetti; Maxime Dufour; Jacques Darcourt; Fabien Almairac; John Coyne; Thierry Virolle; Olivier Humbert; Fanny Burel-Vandenbos
Journal:  PLoS One       Date:  2017-09-22       Impact factor: 3.240

Review 3.  Amino acid PET and MR perfusion imaging in brain tumours.

Authors:  Christian P Filss; Francesco Cicone; Nadim Jon Shah; Norbert Galldiks; Karl-Josef Langen
Journal:  Clin Transl Imaging       Date:  2017-03-13

Review 4.  Contribution of Different Positron Emission Tomography Tracers in Glioma Management: Focus on Glioblastoma.

Authors:  Aurélie Moreau; Olivia Febvey; Thomas Mognetti; Didier Frappaz; David Kryza
Journal:  Front Oncol       Date:  2019-11-01       Impact factor: 6.244

Review 5.  PET Imaging in Neuro-Oncology: An Update and Overview of a Rapidly Growing Area.

Authors:  Antoine Verger; Aurélie Kas; Jacques Darcourt; Eric Guedj
Journal:  Cancers (Basel)       Date:  2022-02-22       Impact factor: 6.639

Review 6.  What Does PET Imaging Bring to Neuro-Oncology in 2022? A Review.

Authors:  Jules Tianyu Zhang-Yin; Antoine Girard; Marc Bertaux
Journal:  Cancers (Basel)       Date:  2022-02-10       Impact factor: 6.639

Review 7.  Applications of Artificial Intelligence Based on Medical Imaging in Glioma: Current State and Future Challenges.

Authors:  Jiaona Xu; Yuting Meng; Kefan Qiu; Win Topatana; Shijie Li; Chao Wei; Tianwen Chen; Mingyu Chen; Zhongxiang Ding; Guozhong Niu
Journal:  Front Oncol       Date:  2022-07-27       Impact factor: 5.738

8.  Case Report: 18F-Fluoro-L-Phenylalanine Positron Emission Tomography Findings and Immunoreactivity for L-Type Amino Acid Transporter 1 in a Dog With Meningioma.

Authors:  Dohee Lee; Taesik Yun; Sanggu Kim; Yoonhoi Koo; Yeon Chae; Soochong Kim; Dongwoo Chang; Mhan-Pyo Yang; Hakhyun Kim; Byeong-Teck Kang
Journal:  Front Vet Sci       Date:  2022-07-15

9.  Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's disease.

Authors:  Julian L Goggi; Lifeng Qiu; Mei Chih Liao; Shivashankar Khanapur; Lingfan Jiang; Ramasamy Boominathan; Siddesh V Hartimath; Peter Cheng; Fui Fong Yong; Vanessa Soh; Xiaozhou Deng; Youshan Melissa Lin; Anna Haslop; Peng Wen Tan; Xiaoxia Zeng; Jolene W L Lee; Zhiwei Zhang; Pragalath Sadasivam; Eng King Tan; Sajinder K Luthra; William D Shingleton; Steve K W Oh; Li Zeng; Edward G Robins
Journal:  Stem Cell Res Ther       Date:  2020-08-08       Impact factor: 6.832
  9 in total

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