Ho Young Hwang1, Kyung-Hwan Kim1, Ki-Bong Kim1, Hyuk Ahn2. 1. Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of Korea. 2. Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address: ahnhyuk@snu.ac.kr.
Abstract
BACKGROUND: Evidence for optimal prosthesis in the tricuspid position is lacking. We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. METHODS: From January 1994 to December 2012, 224 patients (male to female ratio=55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. RESULTS: The ages of the propensity score-matched patients were 54.1±8.7 and 55.3±11.6 years in the MTV and BTV groups, respectively. Early mortality (n=9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups (p=0.897 and p=0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. CONCLUSIONS: Bioprosthetic valve replacement is a valid option for TVR in these relatively young patients because anticoagulation could be avoided without increasing the risks of long-term TVRE.
BACKGROUND: Evidence for optimal prosthesis in the tricuspid position is lacking. We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. METHODS: From January 1994 to December 2012, 224 patients (male to female ratio=55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. RESULTS: The ages of the propensity score-matched patients were 54.1±8.7 and 55.3±11.6 years in the MTV and BTV groups, respectively. Early mortality (n=9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups (p=0.897 and p=0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. CONCLUSIONS: Bioprosthetic valve replacement is a valid option for TVR in these relatively young patients because anticoagulation could be avoided without increasing the risks of long-term TVRE.
Authors: Igor Belluschi; Benedetto Del Forno; Elisabetta Lapenna; Teodora Nisi; Giuseppe Iaci; David Ferrara; Alessandro Castiglioni; Ottavio Alfieri; Michele De Bonis Journal: Front Cardiovasc Med Date: 2018-08-28