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Literature DB >> 24564002

Obesity: the 'huge' problem in cardiovascular diseases.

Abstract

Obesity is an epidemic in the United States. It is an independent risk factor for cardiovascular diseases and associated with reduced life expectancy. The adverse effects are related to direct impact of obesity on cardiovascular system and indirectly through its influence on risk factors. Excessive accumulation of adipose tissue in the myocardium leads to structural and functional alteration. In addition, numerous hormones secreted by adipose tissue create pro-inflammatory and prothrombotic state. This predisposes to coronary heart disease, heart failure, and sudden death. Even those with normal weight but excessive body fat are at risk. Weight reduction and exercise are the main therapeutic options.

Entities: Disease

Mesh：

Substances：
Adipokines

Year: 2013 PMID： 24564002 PMCID： PMC6179812

Source DB: PubMed Journal: Mo Med ISSN： 0026-6620

27 in total

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7 in total

1. Validity of two brief physical activity questionnaires with accelerometers among African-American women.

Authors: Rodney P Joseph; Colleen Keller; Marc A Adams; Barbara E Ainsworth
Journal: Prim Health Care Res Dev Date: 2015-07-16 Impact factor: 1.458

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Journal: Mo Med Date: 2014 Jan-Feb

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Authors: Marta G Novelle; Devin Wahl; Carlos Diéguez; Michel Bernier; Rafael de Cabo
Journal: Ageing Res Rev Date: 2015-01-24 Impact factor: 10.895

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Authors: Mukesh Kumar Sinha; G Arun Maiya; Ana Maria Moga; Shivashankar K N; Ravi Shankar N; Vaishali K
Journal: BMJ Open Date: 2022-04-25 Impact factor: 3.006