Literature DB >> 24563905

Symmetric cyanovinyl-pyridinium triphenylamine: a novel fluorescent switch-on probe for an antiparallel G-quadruplex.

Han Lai, Hai Lai1, Yijie Xiao, Shengyong Yan, Fangfang Tian, Cheng Zhong, Yi Liu, Xiaocheng Weng, Xiang Zhou.   

Abstract

In this study, we present a fluorescent switch-on probe based on a cyanovinyl-pyridinium triphenylamine (CPT) derivative that exhibited a 190-fold increase in fluorescence upon binding to G-quadruplex-forming oligonucleotide 22AG. This probe showed specificity and selectivity towards an antiparallel G-quadruplex, indicating its promising potential in G-quadruplex imaging.

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Year:  2014        PMID: 24563905     DOI: 10.1039/c3an02269b

Source DB:  PubMed          Journal:  Analyst        ISSN: 0003-2654            Impact factor:   4.616


  2 in total

1.  A Nitroxide-Tagged Platinum(II) Complex Enables the Identification of DNA G-Quadruplex Binding Mode.

Authors:  Cui-Xia Xu; Xiaojun Zhang; Yi-Wei Zhou; Hanqiang Wang; Qian Cao; Yong Shen; Liang-Nian Ji; Zong-Wan Mao; Peter Z Qin
Journal:  Chemistry       Date:  2016-02-04       Impact factor: 5.236

2.  A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology.

Authors:  Ming-Hao Hu; Xiao Chen; Shuo-Bin Chen; Tian-Miao Ou; Meicun Yao; Lian-Quan Gu; Zhi-Shu Huang; Jia-Heng Tan
Journal:  Sci Rep       Date:  2015-11-25       Impact factor: 4.379

  2 in total

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