Literature DB >> 24562617

B cell suppression in newborn following treatment of pregnant diffuse large B-cell lymphoma patient with rituximab containing regimen.

Prakas Kumar Mandal1, Tuphan Kanti Dolai, Basab Bagchi, Malay Kumar Ghosh, Sudipta Bose, Maitreyee Bhattacharyya.   

Abstract

Non-Hodgkin lymphoma associated with pregnancy is rare. Rituximab based chemotherapy is now considered the standard of care and considered safe for the treatment of diffuse large B-cell lymphoma (DLBCL) during pregnancy but little is known about its safety profile on the fetus. A 32 y primigravida was diagnosed as DLBCL at 20 wk of gestation. She received rituximab containing chemotherapy with successful pregnancy outcome. Though the baby was absolutely healthy, B-cell was totally absent in the cord blood.

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Year:  2014        PMID： 24562617     DOI： 10.1007/s12098-013-1336-9

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN： 0019-5456            Impact factor:   1.967


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  10 in total

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  10 in total

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