Kyung Eun Han1, Sang Chul Yoon2, Ji Min Ahn3, Sang Min Nam4, R Doyle Stulting5, Eung Kweon Kim2, Kyoung Yul Seo6. 1. Department of Ophthalmology, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital, Chuncheon, South Korea. 2. Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea. 3. Siloam Eye Hospital, Seoul, South Korea. 4. Department of Ophthalmology, CHA Bundang Medical Center, CHA University College of Medicine, Sungnam, South Korea. 5. Stulting Research Center, Woolfson Eye Institute, Atlanta, Georgia, USA. 6. Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: seoky@yuhs.ac.
Abstract
PURPOSE: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. DESIGN: Prospective observational case series. METHODS: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. RESULTS: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). CONCLUSION: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.
PURPOSE: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. DESIGN: Prospective observational case series. METHODS: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. RESULTS: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). CONCLUSION: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.
Authors: Jin Woo Kwon; Yeon Woong Chung; Jin A Choi; Tae Yoon La; Dong Hyun Jee; Yang Kyung Cho Journal: Int J Ophthalmol Date: 2016-02-18 Impact factor: 1.779