Literature DB >> 24561062

Neurogenesis in the striatum of the adult human brain.

Aurélie Ernst1, Kanar Alkass2, Samuel Bernard3, Mehran Salehpour4, Shira Perl5, John Tisdale5, Göran Possnert4, Henrik Druid6, Jonas Frisén7.   

Abstract

In most mammals, neurons are added throughout life in the hippocampus and olfactory bulb. One area where neuroblasts that give rise to adult-born neurons are generated is the lateral ventricle wall of the brain. We show, using histological and carbon-14 dating approaches, that in adult humans new neurons integrate in the striatum, which is adjacent to this neurogenic niche. The neuronal turnover in the striatum appears restricted to interneurons, and postnatally generated striatal neurons are preferentially depleted in patients with Huntington's disease. Our findings demonstrate a unique pattern of neurogenesis in the adult human brain.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2014        PMID： 24561062     DOI： 10.1016/j.cell.2014.01.044

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  357 in total

Review 1.  Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect.

Authors:  Cherkaouia Kibaly; Chi Xu; Catherine M Cahill; Christopher J Evans; Ping-Yee Law
Journal:  Nat Rev Neurosci       Date:  2019-01       Impact factor: 34.870

2.  Functional regulation of FoxO1 in neural stem cell differentiation.

Authors:  D-Y Kim; I Hwang; F L Muller; J-H Paik
Journal:  Cell Death Differ       Date:  2015-10-16       Impact factor: 15.828

Review 3.  New neurons in the adult striatum: from rodents to humans.

Authors:  Dragos Inta; Heather A Cameron; Peter Gass
Journal:  Trends Neurosci       Date:  2015-08-20       Impact factor: 13.837

4.  Adult neurogenesis in the human striatum: possible implications for psychiatric disorders.

Authors:  D Inta; U E Lang; S Borgwardt; A Meyer-Lindenberg; P Gass
Journal:  Mol Psychiatry       Date:  2016-02-16       Impact factor: 15.992

5.  Adult neurogenesis and neurodegenerative diseases: A systems biology perspective.

Authors:  Emrin Horgusluoglu; Kelly Nudelman; Kwangsik Nho; Andrew J Saykin
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2016-02-16       Impact factor: 3.568

6.  Synaptic Regulator α-Synuclein in Dopaminergic Fibers Is Essentially Required for the Maintenance of Subependymal Neural Stem Cells.

Authors:  Ana Perez-Villalba; M Salomé Sirerol-Piquer; Germán Belenguer; Raúl Soriano-Cantón; Ana Belén Muñoz-Manchado; Javier Villadiego; Diana Alarcón-Arís; Federico N Soria; Benjamin Dehay; Erwan Bezard; Miquel Vila; Analía Bortolozzi; Juan José Toledo-Aral; Francisco Pérez-Sánchez; Isabel Fariñas
Journal:  J Neurosci       Date:  2017-12-07       Impact factor: 6.167

7.  Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

Authors:  Taejeong Bae; Livia Tomasini; Jessica Mariani; Bo Zhou; Tanmoy Roychowdhury; Daniel Franjic; Mihovil Pletikos; Reenal Pattni; Bo-Juen Chen; Elisa Venturini; Bridget Riley-Gillis; Nenad Sestan; Alexander E Urban; Alexej Abyzov; Flora M Vaccarino
Journal:  Science       Date:  2017-12-07       Impact factor: 47.728

Review 8.  Noncanonical Sites of Adult Neurogenesis in the Mammalian Brain.

Authors:  David M Feliciano; Angélique Bordey; Luca Bonfanti
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-09-18       Impact factor: 10.005

Review 9.  Neurogenesis and developmental anesthetic neurotoxicity.

Authors:  Eunchai Kang; Daniel A Berg; Orion Furmanski; William M Jackson; Yun Kyoung Ryu; Christy D Gray; C David Mintz
Journal:  Neurotoxicol Teratol       Date:  2016-10-14       Impact factor: 3.763

Review 10.  Cell Replacement to Reverse Brain Aging: Challenges, Pitfalls, and Opportunities.

Authors:  Jean M Hébert; Jan Vijg
Journal:  Trends Neurosci       Date:  2018-03-13       Impact factor: 13.837
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.