Literature DB >> 2455985

Effect of stobadine on stimulated isolated mast cells.

K Drábiková1, J Pecivová, R Nosál.   

Abstract

Stobadine, an antiarrhythmic drug with antihistaminic properties, did not liberate histamine from mast cells in vitro. Compound 48/80-stimulated histamine liberation and degranulation was decreased in the presence of stobadine in a dose-dependent way. The spontaneous as well as stimulated calcium displacement in mast cells was significantly decreased by stobadine. Stobadine most probably possesses a membrane-stabilizing effect on isolated rat mast cells.

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Year:  1988        PMID： 2455985     DOI： 10.1007/bf02142536

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  4 in total

1.  [Alpha-adrenolytic activity of substance DH 1011].

Authors:  R Sotníková; P Gibala; J Drímal
Journal:  Bratisl Lek Listy       Date:  1985-11       Impact factor: 1.278

2.  On the interaction of local anesthetics with mast cells.

Authors:  K Drábiková; R Nosál
Journal:  Agents Actions       Date:  1987-04

3.  On the interaction of beta-adrenoceptor-blocking drugs with isolated mast cells.

Authors:  R Nosál; J Pecivová; K Drábiková
Journal:  Agents Actions       Date:  1985-09

4.  Evidence for intracellular histamine liberation in isolated rat mast cells.

Authors:  R Nosál; J Pecivova; K Drábiková
Journal:  Agents Actions       Date:  1982-12
  4 in total

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