Literature DB >> 24557629

Not asthma, but GERD: case report.

Zhonggao Wang1.   

Abstract

Asthma is a disorder of the lungs characterized by increased responsiveness of the airways, as manifested by episodes of wheezing and increased resistance to expiratory airflow because of varying degrees of smooth muscle contraction, edema of the mucosa, and mucus in the lumen of the bronchi and bronchioles. The stimuli vary widely and include antigens, infection, air pollutants, respiratory tract irrtants, exercise, and emotional factors. This condition is completely different from distress breathing because of laryngotracheal spasm. One of its causes is the gastric content reflux through the pharynx to the larynx because of gastroesophageal reflux disease (GERD), in addition to the typical human avian flu that may cause immediate suffocation by laryngospasm owing to acute larygotrachitis. A patient suffered from GERD without esophageal symptoms, which was diagnosed and treated as bronchial asthma during his five emergency admissions. The admissions were because of episodic attacks of severe air hunger owing to an extreme throat tightening. The patient was being treated for as long as two years. After the correct diagnosis was made and treatment of laporascopic fundaplication was performed, the longstanding "bronchial asthma", after all, completely disappeared. The concept of "not asthma, but GERD" seems undervalued, unappreciated, even misunderstood among patients with intractable asthma. Therefore, such a case is reported in detail, similar cases are mentioned briefly as well, and a mechanism responsible for GERD-originated larryngo-or laryngotracho-spasm is proposed.

Entities:  

Year:  2007        PMID: 24557629     DOI: 10.1007/s11684-007-0022-6

Source DB:  PubMed          Journal:  Front Med China        ISSN: 1673-7342


  11 in total

1.  Medical and surgical treatment of nonallergic asthma associated with gastroesophageal reflux.

Authors:  A Larrain; E Carrasco; F Galleguillos; R Sepulveda; C E Pope
Journal:  Chest       Date:  1991-06       Impact factor: 9.410

2.  [The relation of GERD, bronchial asthma and the upper respiratory tract].

Authors:  Z Matyásová; B Novotná; M Matulová; J Dolina; R Kroupa; Z Láníková; V Znojil; A Hep; P Dite
Journal:  Vnitr Lek       Date:  2005-12

3.  Surgical treatment of gastroesophageal reflux in ten patients with severe asthma.

Authors:  C Tardif; G Nouvet; P Denis; R Tombelaine; P Pasquis
Journal:  Respiration       Date:  1989       Impact factor: 3.580

Review 4.  The effects of antireflux surgery on asthmatics with gastroesophageal reflux.

Authors:  S K Field; G A Gelfand; S D McFadden
Journal:  Chest       Date:  1999-09       Impact factor: 9.410

5.  Relationship between asthma and gastro-oesophageal reflux: significance of endoscopic grade of reflux oesophagitis in adult asthmatics.

Authors:  H Nakase; T Itani; J Mimura; T Kawasaki; H Komori; H Tomioka; T Chiba
Journal:  J Gastroenterol Hepatol       Date:  1999-07       Impact factor: 4.029

Review 6.  Gastroesophageal reflux disease in asthma: effects of medical and surgical antireflux therapy on asthma control.

Authors:  D J Bowrey; J H Peters; T R DeMeester
Journal:  Ann Surg       Date:  2000-02       Impact factor: 12.969

Review 7.  Extraoesophageal manifestations of gastro-oesophageal reflux.

Authors:  J Poelmans; J Tack
Journal:  Gut       Date:  2005-10       Impact factor: 23.059

Review 8.  Gastro-oesophageal reflux disease in Asia.

Authors:  K L Goh; C S Chang; K M Fock; M Ke; H J Park; S K Lam
Journal:  J Gastroenterol Hepatol       Date:  2000-03       Impact factor: 4.029

Review 9.  GERD: the potential for endoscopic intervention.

Authors:  George Triadafilopoulos
Journal:  Dig Dis       Date:  2004       Impact factor: 2.404

10.  Pathogenesis of chronic persistent cough associated with gastroesophageal reflux.

Authors:  A J Ing; M C Ngu; A B Breslin
Journal:  Am J Respir Crit Care Med       Date:  1994-01       Impact factor: 21.405

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