Literature DB >> 24557480

Complete C4 vertebral body destruction: a dramatic finding in a patient with a new diagnosis of myeloma.

Andrew James Berg1, Miguel Hernandez, Chandra Bhatia.   

Abstract

We report the case of a 60-year-old woman who presented to accident and emergency with left arm and neck pain. She had reported these symptoms to her general practitioner over the preceding weeks but no imaging was obtained. Radiographs revealed a pathological lesion in her left humerus. On review in the Orthopaedic Fracture Clinic radiographs of the cervical spine were obtained and showed complete destruction of the C4 vertebral body. She underwent corpectomy and stabilisation. Tissue diagnosis confirmed myeloma and she is now under the care of the haematologists receiving chemotherapy and radiotherapy. Myeloma is known to cause severe destructive lesions. Through the dramatic radiographic images this case serves as a reminder to clinicians to obtain imaging of patients with a new or existing diagnosis of malignancy, who show symptoms of skeletal pain, as lesions requiring emergency management may be present.

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Mesh:

Year:  2014        PMID: 24557480      PMCID: PMC3931956          DOI: 10.1136/bcr-2013-203108

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  Vertebroplasty and kyphoplasty for spinal metastases.

Authors:  John H Chi; Ziya L Gokaslan
Journal:  Curr Opin Support Palliat Care       Date:  2008-03       Impact factor: 2.302

2.  Research on safety of single-stage multisegmental thoracolumbar percutaneous balloon vertebroplasty.

Authors:  KaiNan Li; Bao Yao
Journal:  J Spinal Disord Tech       Date:  2014-08

3.  Multiple myeloma: surgery of the spine: retrospective analysis of 27 patients.

Authors:  Hans Roland Dürr; Bernd Wegener; Andreas Krödel; Peter Ernst Müller; Volkmar Jansson; Hans Jürgen Refior
Journal:  Spine (Phila Pa 1976)       Date:  2002-02-01       Impact factor: 3.468

Review 4.  Bone destruction and hypercalcemia in plasma cell myeloma.

Authors:  G R Mundy; D R Bertolini
Journal:  Semin Oncol       Date:  1986-09       Impact factor: 4.929

Review 5.  The treatment of multiple myeloma.

Authors:  R Alexanian; M Dimopoulos
Journal:  N Engl J Med       Date:  1994-02-17       Impact factor: 91.245

6.  Percutaneous vertebroplasty relieves pain in metastatic cervical fractures.

Authors:  S Masala; G C Anselmetti; M Muto; M Mammucari; T Volpi; G Simonetti
Journal:  Clin Orthop Relat Res       Date:  2011-03       Impact factor: 4.176

7.  Fracture risk with multiple myeloma: a population-based study.

Authors:  L Joseph Melton; Robert A Kyle; Sara J Achenbach; Ann L Oberg; S Vincent Rajkumar
Journal:  J Bone Miner Res       Date:  2004-11-29       Impact factor: 6.741

8.  Radiofrequency-targeted vertebral augmentation for the treatment of vertebral compression fractures as a result of multiple myeloma.

Authors:  Eren Erdem; Sertac Akdol; Adewumi Amole; Katy Fryar; Robert W Eberle
Journal:  Spine (Phila Pa 1976)       Date:  2013-07-01       Impact factor: 3.468

9.  Primary bone tumors of adulthood.

Authors:  Harvey E L Teo; Wilfrid C G Peh
Journal:  Cancer Imaging       Date:  2004-03-29       Impact factor: 3.909

  9 in total
  1 in total

1.  Pathological burst fracture in the cervical spine with negative red flags: a case report.

Authors:  Jocelyn Cox; Chris DeGraauw; Erik Klein
Journal:  J Can Chiropr Assoc       Date:  2016-03
  1 in total

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