Literature DB >> 24556799

A subcutaneous paraspinal yolk sac tumor in a child.

Sibel A Tekgündüz1, Ceyhun Bozkurt, Gürses Sahin, Sema Apaydin, Ayşe C Ören, Eda Balkaya, Ayşe U Ertem.   

Abstract

A 3-year-old girl underwent a surgery at an external center on July 2011 for a swelling in the left lumbar paravertebral subcutaneous region. The mass was completely excised and the pathologic diagnosis was a yolk sac tumor (YST). Laboratory tests revealed a serum α-fetoprotein level of 278 IU/mL. Investigations using bone scintigraphy and magnetic resonance imaging revealed a scar tissue at the surgical site and lesions indicating metastasis at the lumbar first, second, third, and fifth vertebra. The patient was administered 5 cycles of PEB (cisplatin, etoposide, bleomycin) treatment. The serum α-fetoprotein was 3 IU/mL after the treatment. The lumbar magnetic resonance imaging and bone scintigraphy results were normal. The patient continues to be in remission since June 2012. YSTs are most commonly seen in the testis, ovary, and sacrococcygeal regions. Atypical locations have been reported with the primary lesion in the stomach, diaphragm, omentum, sino-nasal region, cranial base, lungs, vagina, and penis. Our case is probably a YST with an atypical location derived from preliminary cells left under the skin because of a migration defect.

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Year:  2014        PMID: 24556799     DOI: 10.1097/MPH.0b013e31829d140a

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  2 in total

1.  Yolk sac tumor in the abdominal wall of an 18-month-old girl: a case report.

Authors:  Machiel van den Akker; Dirk Vervloessem; An Huybrechs; Sabine Declercq; Jutte van der Werff Ten Bosch
Journal:  J Med Case Rep       Date:  2017-02-20

2.  Fine needle aspiration (FNA) of subcutaneous lesion: A diagnostic dilemma on cytology.

Authors:  Manjari Kishore; Purnima Malhotra; Manju Kaushal; Preeti Singh; Neeti Kapur
Journal:  Cytojournal       Date:  2019-08-22       Impact factor: 2.091

  2 in total

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