Literature DB >> 2455601

Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities.

M Katan1, R W Kriz, N Totty, R Philp, E Meldrum, R A Aldape, J L Knopf, P J Parker.   

Abstract

Protein sequence analysis of a bovine brain phosphoinositide-specific phospholipase C (PI-PLC; PLC-154) has permitted the isolation of a cDNA that appears to code for this protein. Transient expression of this cDNA in COS-1 cells demonstrates that the cDNA encodes a functional phospholipase C that migrates at approximately 150,000 daltons. A transcript of approximately 7 kb is observed in RNA derived from bovine brain and a related transcript of the same size is present in certain human cell lines. Southern blot analysis indicates that one or possibly two genes hybridize with a PLC-154 probe. Regions of homology between PLC-154 and the previously described PLC-148 allow the assignment of a putative catalytic domain to the central region of PLC-154.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2455601     DOI： 10.1016/0092-8674(88)90549-1

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  26 in total

Review 1.  Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.

Authors:  S Cockcroft; G M Thomas
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

2.  A novel Bacillus subtilis gene involved in negative control of sporulation and degradative-enzyme production.

Authors:  M Honjo; A Nakayama; K Fukazawa; K Kawamura; K Ando; M Hori; Y Furutani
Journal:  J Bacteriol       Date:  1990-04       Impact factor: 3.490

3.  Development of muscarinic-cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a switch in guanine-nucleotide-binding protein coupling.

Authors:  J V Barnett; S M Shamah; B Lassegue; K K Griendling; J B Galper
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

4.  The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.

Authors:  C A Koch; M Moran; I Sadowski; T Pawson
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

Review 5.  The putative molecular mechanism(s) responsible for the enhanced inositol phosphate synthesis by excitatory amino acids: an overview.

Authors:  M Récasens; J Guiramand; M Vignes
Journal:  Neurochem Res       Date:  1991-06       Impact factor: 3.996

6.  Isolation and characterization of a gamma-type phosphoinositide-specific phospholipase C (PLC-gamma 2).

Authors:  Y Homma; Y Emori; F Shibasaki; K Suzuki; T Takenawa
Journal:  Biochem J       Date:  1990-07-01       Impact factor: 3.857

7.  Electroconvulsive treatment: effects on phospholipase C activity and GTP binding activity in rat brain.

Authors:  A Nishida; H Kaiya; T Tohmatsu; S Wakabayashi; Y Nozawa
Journal:  J Neural Transm Gen Sect       Date:  1990

8.  Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells.

Authors:  M I Wahl; N E Olashaw; S Nishibe; S G Rhee; W J Pledger; G Carpenter
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

9.  Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

Authors:  D Kitamura; H Kaneko; Y Miyagoe; T Ariyasu; T Watanabe
Journal:  Nucleic Acids Res       Date:  1989-11-25       Impact factor: 16.971

10.  Distinctive subtypes of bovine phospholipase C that have preferential expression in the retina and high homology to the norpA gene product of Drosophila.

Authors:  P A Ferreira; R D Shortridge; W L Pak
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.