OBJECTIVE: Fibrolamellar hepatocellular carcinoma (HCC) is a rare primary liver tumor, which significantly differs from conventional HCC. This article reviews the molecular cytogenetics, pathology, imaging features, and management of this relatively rare tumor. CONCLUSION: Fibrolamellar HCC predominantly occurs in young patients without underlying hepatitis or cirrhosis. Serum α-fetoproteins are not elevated in most cases, and hence imaging plays an important role in diagnosis, staging, and surveillance.
OBJECTIVE:Fibrolamellar hepatocellular carcinoma (HCC) is a rare primary liver tumor, which significantly differs from conventional HCC. This article reviews the molecular cytogenetics, pathology, imaging features, and management of this relatively rare tumor. CONCLUSION: Fibrolamellar HCC predominantly occurs in young patients without underlying hepatitis or cirrhosis. Serum α-fetoproteins are not elevated in most cases, and hence imaging plays an important role in diagnosis, staging, and surveillance.
Authors: Richard C Semelka; Nadesan Nimojan; Saman Chandana; Miguel Ramalho; Suzanne L Palmer; Danielle DeMulder; Carolina Parada Villavicencio; John Woosley; Bonnie L Garon; Reena C Jha; Frank H Miller; Ersan Altun Journal: Eur Radiol Date: 2017-10-27 Impact factor: 5.315
Authors: Nicolas A Villa; Rahul Pannala; Douglas O Faigel; Danielle J Haakinson; Nitin Katariya; Ramesh Ramanathan; Dawn Jaroszewski; Thomas K Lidner; Thomas Byrne Journal: Case Rep Gastroenterol Date: 2015-07-29