Literature DB >> 24554831

Antithymocyte globulin induced recurrent seizures in a case of severe aplastic anemia.

Sanjeev Kumar Sharma1, Pawan Kumar Singh1, Tulika Seth1, Pravas Mishra1, Manoranjan Mahapatra1.   

Abstract

Antithymocyte globulin (ATG) has been the standard immuno suppressive therapy for aplastic anemia. ATG significantly improves survival and response rates vary between 40 and 70 %. Mild side effects are common but recurrent seizures have rarely been reported with ATG.

Entities:  

Keywords:  Antithymocyte globulin; Aplastic anemia; Seizures

Year:  2012        PMID： 24554831      PMCID： PMC3921336          DOI： 10.1007/s12288-012-0183-6

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  11 in total

Review 1.  Neuroactive steroids and seizure susceptibility.

Authors:  S Beyenburg; B Stoffel-Wagner; J Bauer; M Watzka; I Blümcke; F Bidlingmaier; C E Elger
Journal:  Epilepsy Res       Date:  2001-05       Impact factor: 3.045

2.  Antithymocyte globulin has limited efficacy and substantial toxicity in unselected anemic patients with myelodysplastic syndrome.

Authors:  David P Steensma; Angela Dispenzieri; S Breanndan Moore; Georgene Schroeder; Ayalew Tefferi
Journal:  Blood       Date:  2002-10-31       Impact factor: 22.113

Review 3.  Cyclosporine neurotoxicity: a review.

Authors:  J M Gijtenbeek; M J van den Bent; C J Vecht
Journal:  J Neurol       Date:  1999-05       Impact factor: 4.849

4.  Treatment of aplastic anemia: results with bone marrow transplantation, antithymocyte globulin, and a monoclonal anti-T cell antibody.

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Journal:  Prog Clin Biol Res       Date:  1984

Review 5.  Neurotoxicity of calcineurin inhibitors: impact and clinical management.

Authors:  W O Bechstein
Journal:  Transpl Int       Date:  2000       Impact factor: 3.782

6.  Cyclosporine induces epileptiform activity in an in vitro seizure model.

Authors:  M Wong; K A Yamada
Journal:  Epilepsia       Date:  2000-03       Impact factor: 5.864

7.  Cyclosporine therapy of aplastic anaemia, congenital and acquired red cell aplasia.

Authors:  E M Leonard; E Raefsky; P Griffith; J Kimball; A W Nienhuis; N S Young
Journal:  Br J Haematol       Date:  1989-06       Impact factor: 6.998

Review 8.  Corticosteroids enhance convulsion susceptibility via central mineralocorticoid receptors.

Authors:  A J Roberts; L D Keith
Journal:  Psychoneuroendocrinology       Date:  1995       Impact factor: 4.905

9.  Treatment of aplastic anemia with antithymocyte globulin, high-dose corticosteroids, and androgens.

Authors:  K Doney; R Storb; C D Buckner; R McGuffin; R Witherspoon; H J Deeg; F R Appelbaum; K M Sullivan; E D Thomas
Journal:  Exp Hematol       Date:  1987-03       Impact factor: 3.084

10.  Antithoracic duct lymphocyte globulin therapy of severe aplastic anemia.

Authors:  B Camitta; R J O'Reilly; L Sensenbrenner; J Rappeport; R Champlin; K Doney; C August; R G Hoffmann; D Kirkpatrick; R Stuart; G Santos; R Parkman; R P Gale; R Storb; D Nathan
Journal:  Blood       Date:  1983-10       Impact factor: 22.113
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