Literature DB >> 24554680

Sepsis-induced purpura fulminans caused by Pasteurella multocida.

Lisa Borges1, Nelson Oliveira, Isabel Cássio, Humberto Costa.   

Abstract

A 52-year-old man was admitted with a cutaneous rash associated with septic shock and multiorganic failure, 6 days after a dog bite. He was started on empiric antibiotherapy and supportive measures. The patient's condition aggravated, with need for invasive mechanical ventilation and intermittent haemodialysis, and evolution from a petechiae-like rash to purpura and gangrene, culminating in bilateral lower limb amputation. The blood cultures revealed only Pasteurella multocida, after 10 days of incubation. P multocida infection is a rare cause of soft tissue infection that subsides with oral antibiotherapy. Infections causing sepsis are rare and appear in immunocompromised patients. Purpura fulminans induced by sepsis is a rare, life-threatening disorder. This syndrome should be recognised promptly, so early treatment is instituted. We found no case reports of purpura fulminans caused by Pasteurella infections in our literature review.

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Year:  2014        PMID: 24554680      PMCID: PMC3931955          DOI: 10.1136/bcr-2013-202441

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

Review 1.  Infectious purpura fulminans: diagnosis and treatment.

Authors:  O P Smith; B White
Journal:  Br J Haematol       Date:  1999-02       Impact factor: 6.998

Review 2.  Purpura fulminans: recognition, diagnosis and management.

Authors:  E Chalmers; P Cooper; K Forman; C Grimley; K Khair; A Minford; M Morgan; A D Mumford
Journal:  Arch Dis Child       Date:  2011-01-12       Impact factor: 3.791

3.  Surgical management of acute infectious purpura fulminans.

Authors:  Michelle C Roughton; Shailesh Agarwal; Lawrence J Gottlieb
Journal:  J Burn Care Res       Date:  2011 Mar-Apr       Impact factor: 1.845

4.  Sepsis-associated purpura fulminans in adults.

Authors:  G Gamper; E Oschatz; H Herkner; G Paul; H Burgmann; K Janata; M Röggla; A N Laggner
Journal:  Wien Klin Wochenschr       Date:  2001-02-15       Impact factor: 1.704

5.  The protective effect of brachial plexus palsy in purpura fulminans.

Authors:  T M Willis; R J Hopp; J R Romero; P D Larsen
Journal:  Pediatr Neurol       Date:  2001-05       Impact factor: 3.372

6.  Human skin allografts as a useful adjunct in the treatment of purpura fulminans.

Authors:  S Gaucher; J Stéphanazzi; M Jarraya
Journal:  J Wound Care       Date:  2010-08       Impact factor: 2.072

7.  The surgical implications of purpura fulminans.

Authors:  J R Cohen; R Lackner; A Keller; B Douglas
Journal:  Ann Vasc Surg       Date:  1990-05       Impact factor: 1.466

Review 8.  Purpura fulminans and symmetrical peripheral gangrene caused by Capnocytophaga canimorsus (formerly DF-2) septicemia--a complication of dog bite.

Authors:  B J Kullberg; R G Westendorp; J W van 't Wout; A E Meinders
Journal:  Medicine (Baltimore)       Date:  1991-09       Impact factor: 1.889

9.  Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology.

Authors:  M Levi; C H Toh; J Thachil; H G Watson
Journal:  Br J Haematol       Date:  2009-02-12       Impact factor: 6.998

10.  Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies.

Authors:  Jean-Louis Vincent; Simon Nadel; Demetrios J Kutsogiannis; R T Noel Gibney; S Betty Yan; Virginia L Wyss; Joan E Bailey; Carol L Mitchell; Samiha Sarwat; Stephen M Shinall; Jonathan M Janes
Journal:  Crit Care       Date:  2005-05-17       Impact factor: 9.097

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  3 in total

1.  [Sepsis-associated Purpura Fulminans International Registry--Europe (SAPFIRE)].

Authors:  F M Brunkhorst; V Patchev
Journal:  Med Klin Intensivmed Notfmed       Date:  2014-10-29       Impact factor: 0.840

2.  Purpura fulminans and severe sepsis due to Pasteurella multocida infection in an immunocompetent patient.

Authors:  Monoj Kumar Konda; Stephanie Chang; Mathew Zaccheo
Journal:  BMJ Case Rep       Date:  2016-06-13

Review 3.  Surgical outcomes in adults with purpura fulminans: a systematic review and patient-level meta-synthesis.

Authors:  Kevin M Klifto; Caresse F Gurno; Michael J Grzelak; Stella M Seal; Mohammed Asif; C Scott Hultman; Julie A Caffrey
Journal:  Burns Trauma       Date:  2019-10-18
  3 in total

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