Literature DB >> 24554532

The Australian, US, Scandinavian Imaging Exchange (AUSSIE): an innovative, virtually-integrated health research network embedded in health care.

Jeffrey Cl Looi1, Dennis Velakoulis2, Mark Walterfang2, Nellie Georgiou-Karistianis3, Matthew D Macfarlane4, Brian D Power5, Christer Nilsson6, Martin Styner7, Paul M Thompson8, Danielle Van Westen9, Fiona A Wilkes10, Lars-Olof Wahlund11.   

Abstract

OBJECTIVE: To describe the development, design and function of an innovative international clinical research network for neuroimaging research, based in Australia, within a joint state health service/medical school. This Australian, US, Scandinavian Imaging Exchange (AUSSIE) network focuses upon identifying neuroimaging biomarkers for neuropsychiatric and neurodegenerative disease.
METHODS: We describe a case study of the iterative development of the network, identifying characteristic features and methods which may serve as potential models for virtual clinical research networks. This network was established to analyse clinically-derived neuroimaging data relevant to neuropsychiatric and neurodegenerative disease, specifically in relation to subcortical brain structures.
RESULTS: The AUSSIE network has harnessed synergies from the individual expertise of the component groups, primarily clinical neuroscience researchers, to analyse a variety of clinical data.
CONCLUSION: AUSSIE is an active virtual clinical research network, analogous to a connectome, which is embedded in health care and has produced significant research, advancing our understanding of neuropsychiatric and neurodegenerative disease through the lens of neuroimaging. © The Royal Australian and New Zealand College of Psychiatrists 2014.

Entities:  

Keywords:  AUSSIE; clinical research; clinical research network; collaboration; imaging; international; neurodegenerative disease; neuroimaging; neuropsychiatric disease

Year:  2014        PMID: 24554532      PMCID: PMC4276529          DOI: 10.1177/1039856214523494

Source DB:  PubMed          Journal:  Australas Psychiatry        ISSN: 1039-8562            Impact factor:   1.369


  14 in total

1.  Volumetrics of the caudate nucleus: reliability and validity of a new manual tracing protocol.

Authors:  Jeffrey Chee Leong Looi; Olof Lindberg; Benny Liberg; Vanessa Tatham; Rajeev Kumar; Jerome Maller; Ellen Millard; Perminder Sachdev; Göran Högberg; Marco Pagani; Lisa Botes; Eva-Lena Engman; Yi Zhang; Leif Svensson; Lars-Olof Wahlund
Journal:  Psychiatry Res       Date:  2008-07-25       Impact factor: 3.222

2.  Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease mild cognitive impairment, and elderly controls.

Authors:  Jonathan H Morra; Zhuowen Tu; Liana G Apostolova; Amity E Green; Christina Avedissian; Sarah K Madsen; Neelroop Parikshak; Xue Hua; Arthur W Toga; Clifford R Jack; Michael W Weiner; Paul M Thompson
Journal:  Neuroimage       Date:  2008-07-16       Impact factor: 6.556

Review 3.  Striatal morphology as a biomarker in neurodegenerative disease.

Authors:  J C L Looi; M Walterfang
Journal:  Mol Psychiatry       Date:  2012-05-15       Impact factor: 15.992

4.  Shape alterations in the striatum in chorea-acanthocytosis.

Authors:  Mark Walterfang; Jeffrey Chee Leong Looi; Martin Styner; Ruth H Walker; Adrian Danek; Marc Niethammer; Andrew Evans; Katya Kotschet; Guilherme R Rodrigues; Andrew Hughes; Dennis Velakoulis
Journal:  Psychiatry Res       Date:  2011-03-05       Impact factor: 3.222

5.  Hippocampal shape analysis in Alzheimer's disease and frontotemporal lobar degeneration subtypes.

Authors:  Olof Lindberg; Mark Walterfang; Jeffrey C L Looi; Nikolai Malykhin; Per Ostberg; Bram Zandbelt; Martin Styner; Beatriz Paniagua; Dennis Velakoulis; Eva Orndahl; Lars-Olof Wahlund
Journal:  J Alzheimers Dis       Date:  2012       Impact factor: 4.472

6.  Morphometric analysis of subcortical structures in progressive supranuclear palsy: In vivo evidence of neostriatal and mesencephalic atrophy.

Authors:  Jeffrey C L Looi; Matthew D Macfarlane; Mark Walterfang; Martin Styner; Dennis Velakoulis; Jimmy Lätt; Danielle van Westen; Christer Nilsson
Journal:  Psychiatry Res       Date:  2011-09-06       Impact factor: 3.222

7.  Pontine-to-midbrain ratio indexes ocular-motor function and illness stage in adult Niemann-Pick disease type C.

Authors:  M Walterfang; M D Macfarlane; J C L Looi; L Abel; E Bowman; M C Fahey; P Desmond; D Velakoulis
Journal:  Eur J Neurol       Date:  2012-03       Impact factor: 6.089

8.  Caudate volumes in public transportation workers exposed to trauma in the Stockholm train system.

Authors:  Jeffrey Chee Leong Looi; Jerome Joseph Maller; Marco Pagani; Göran Högberg; Olof Lindberg; Benny Liberg; Lisa Botes; Eva-Lena Engman; Yi Zhang; Leif Svensson; Lars-Olof Wahlund
Journal:  Psychiatry Res       Date:  2009-01-26       Impact factor: 3.222

9.  Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: results from a subset of the LADIS study.

Authors:  Matthew D Macfarlane; Jeffrey C L Looi; Mark Walterfang; Gabriela Spulber; Dennis Velakoulis; Martin Styner; Milita Crisby; Eva Orndahl; Timo Erkinjuntti; Gunhild Waldemar; Ellen Garde; Michael G Hennerici; Hansjörg Bäzner; Christian Blahak; Anders Wallin; Lars-Olof Wahlund
Journal:  Am J Geriatr Psychiatry       Date:  2013-08-01       Impact factor: 4.105

10.  Caudate nucleus volumes in stroke and vascular dementia.

Authors:  Jeffrey Chee Leong Looi; Vanessa Tatham; Rajeev Kumar; Jerome J Maller; Ellen Millard; Wei Wen; Xiaohua Chen; Henry Brodaty; Perminder Sachdev
Journal:  Psychiatry Res       Date:  2009-09-30       Impact factor: 3.222

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