Ana Lúcia do Rêgo Rodrigues Costa1, Edward Araujo Júnior2, José Wellington de Oliveira Lima1, Fabrício da Silva Costa3. 1. Universidade Estadual do Ceará, FortalezaCE, Brasil, Universidade Estadual do Ceará - UECE - Fortaleza (CE), Brasil. 2. Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Obstetrícia, São PauloSP, Brasil, Departamento de Obstetrícia da Escola Paulista de Medicina; Universidade Federal de São Paulo - UNIFESP - São Paulo (SP), Brasil. 3. University of Melbourne, Department of Obstetrics and Gynecology, Royal Women's Hospital, Melbourne, Austrália, Department of Perinatal Medicine; Royal Women's Hospital and Department of Obstetrics and Gynecology; University of Melbourne - Melbourne, Austrália.
Abstract
PURPOSE: To evaluate the maternal risk factors that require newborn assistance in neonatal Intensive Care Units (ICU). METHODS: A prospective observational case-control study was conducted on 222 pregnant women (1:1 case-control ratio) attended at a public maternity. The following variables were analyzed in the puerperae: age at menarche, age at first sexual intercourse, history of chronic diseases, habits, prenatal care, obstetric history, clinical complications during pregnancy and childbirth, and sociodemographic variables. The variables of the newborns were: Apgar scores, gestational age, birth weight, presence or absence of malformation, need for resuscitation, and complications during the first 24 hours. Proportions were compared using the Fisher exact test or the Person γ2 test. Multivariable models were developed by logistic regression analysis using adjusted Odds Ratio with a 95% confidence interval (CI). RESULTS: Regarding reproductive history, ≥3 pregnancies and 2 or 3 previous cesareans were sytatistically significant (p=0.0 and 0.0, respectively). Among the complications that required assistance in the neonatal ICU, prematurity was responsible for 61 cases (55.5%), followed by risk of intrapartum infection in 46 cases (41.8%). Regarding the maternal history, the presence of hypertensive disease showed statistical significance (p=0.0). Premature rupture of membranes was strongly associated with the need for the neonatal ICU (Odds Ratio - OR=6.1, 95%CI 2.6-14.4). CONCLUSIONS: Premature rupture of membranes and hypertensive disease should receive special attention in prenatal care due to their strong association with newborns requiring assistance in the neonatal ICU.
PURPOSE: To evaluate the maternal risk factors that require newborn assistance in neonatal Intensive Care Units (ICU). METHODS: A prospective observational case-control study was conducted on 222 pregnant women (1:1 case-control ratio) attended at a public maternity. The following variables were analyzed in the puerperae: age at menarche, age at first sexual intercourse, history of chronic diseases, habits, prenatal care, obstetric history, clinical complications during pregnancy and childbirth, and sociodemographic variables. The variables of the newborns were: Apgar scores, gestational age, birth weight, presence or absence of malformation, need for resuscitation, and complications during the first 24 hours. Proportions were compared using the Fisher exact test or the Person γ2 test. Multivariable models were developed by logistic regression analysis using adjusted Odds Ratio with a 95% confidence interval (CI). RESULTS: Regarding reproductive history, ≥3 pregnancies and 2 or 3 previous cesareans were sytatistically significant (p=0.0 and 0.0, respectively). Among the complications that required assistance in the neonatal ICU, prematurity was responsible for 61 cases (55.5%), followed by risk of intrapartum infection in 46 cases (41.8%). Regarding the maternal history, the presence of hypertensive disease showed statistical significance (p=0.0). Premature rupture of membranes was strongly associated with the need for the neonatal ICU (Odds Ratio - OR=6.1, 95%CI 2.6-14.4). CONCLUSIONS:Premature rupture of membranes and hypertensive disease should receive special attention in prenatal care due to their strong association with newborns requiring assistance in the neonatal ICU.