| Literature DB >> 24553893 |
Cathal J Moran1, Cecilia Pascual-Garrido1, Susan Chubinskaya2, Hollis G Potter1, Russell F Warren1, Brian J Cole3, Scott A Rodeo1.
Abstract
➤ Novel (i.e., quantitative and semiquantitative) cartilage imaging techniques can evaluate cartilage composition to augment information obtained from traditional magnetic resonance imaging sequences that detail morphology.➤ A well-defined role for drugs leading to chondroprotection has not yet been determined.➤ Shortcomings of bone marrow stimulation include limited production of hyaline repair tissue, unpredictable repair cartilage volume, and a negative impact on later cellular transplantation if required.➤ The role of biological augments, such as cellular concentrates or platelet-rich plasma, remains undefined. When their use is reported in the literature, it is important that their process of production and characterization be detailed.➤ Rehabilitation programs, incorporating controlled exercise and progressive partial weight-bearing, are an important part of cartilage repair surgery and should be detailed in reports on operative techniques applied.➤ Malalignment, meniscal injury, and ligament deficiency should be corrected in a staged or concomitant fashion to reduce the overall likelihood of mechanical failure in cartilage repair surgery.Entities:
Mesh:
Year: 2014 PMID: 24553893 DOI: 10.2106/JBJS.L.01329
Source DB: PubMed Journal: J Bone Joint Surg Am ISSN: 0021-9355 Impact factor: 5.284