Literature DB >> 24553677

Toll-like receptor-4 signaling: a new potential therapeutic pathway for rheumatoid arthritis.

Xiaofeng Li1, Tao Xu, Yarui Wang, Cheng Huang, Jun Li.   

Abstract

The Toll-like receptor-4 signaling (TLR-4) has been found to be over-expressed in rheumatoid arthritis (RA) synovium. Furthermore, it regulates the expression of pro-inflammatory cytokines. Based on the current evidences, TLR-4 may be a new potential therapeutic pathway for RA.

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Year:  2014        PMID： 24553677     DOI： 10.1007/s00296-013-2890-1

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  8 in total

Review 1.  Rheumatoid arthritis.

Authors:  M Feldmann; F M Brennan; R N Maini
Journal:  Cell       Date:  1996-05-03       Impact factor: 41.582

2.  Bauhinia championii extraction treatment of collagen-induced arthritis via downregulation of the expression of TLR4, MyD88 and NF-κB.

Authors:  Wei Xu; Kedan Chu; Huang Li; Yuqin Zhang; Mingqing Huang; Haiyin Zheng; Mei Sha; Xun Zhang; Lidian Chen
Journal:  Am J Chin Med       Date:  2013       Impact factor: 4.667

3.  Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

Authors:  Shahla Abdollahi-Roodsaz; Leo A B Joosten; Marije I Koenders; Isabel Devesa; Mieke F Roelofs; Timothy R D J Radstake; Marleen Heuvelmans-Jacobs; Shizuo Akira; Martin J H Nicklin; Fátima Ribeiro-Dias; Wim B van den Berg
Journal:  J Clin Invest       Date:  2008-01       Impact factor: 14.808

4.  Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population.

Authors:  Hongju Yang; Chuanyu Wei; Qin Li; Tao Shou; Yan Yang; Chunjie Xiao; Min Yu; Ming Li; Zhili Yang; Jieying Zhang; Bingrong Zheng
Journal:  Rheumatol Int       Date:  2012-11-06       Impact factor: 2.631

5.  Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis.

Authors:  Caroline Ospelt; Fabia Brentano; Yvonne Rengel; Joanna Stanczyk; Christoph Kolling; Paul P Tak; Renate E Gay; Steffen Gay; Diego Kyburz
Journal:  Arthritis Rheum       Date:  2008-12

6.  MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes.

Authors:  Lucas Philippe; Ghada Alsaleh; Angélique Pichot; Eleonore Ostermann; Guy Zuber; Benoit Frisch; Jean Sibilia; Sébastien Pfeffer; Seiamak Bahram; Dominique Wachsmann; Philippe Georgel
Journal:  Ann Rheum Dis       Date:  2012-10-20       Impact factor: 19.103

7.  Increased responsiveness to toll-like receptor 4 stimulation in peripheral blood mononuclear cells from patients with recent onset rheumatoid arthritis.

Authors:  M L Kowalski; A Wolska; J Grzegorczyk; J Hilt; M Jarzebska; M Drobniewski; M Synder; M Kurowski
Journal:  Mediators Inflamm       Date:  2008       Impact factor: 4.711

8.  Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB-mediated matrix metalloproteinase-9 expression.

Authors:  Guoqing Li; Dan Liu; Yu Zhang; Yayun Qian; Hua Zhang; Shiyu Guo; Masataka Sunagawa; Tadashi Hisamitsu; Yanqing Liu
Journal:  PLoS One       Date:  2013-07-04       Impact factor: 3.240
  8 in total
  1 in total

1.  Direct tissue-sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients.

Authors:  Daniela Amaral-Silva; Rute Gonçalves; Rita C Torrão; Rita Torres; Sandra Falcão; Maria João Gonçalves; Maria Paula Araújo; Maria José Martins; Carina Lopes; Agna Neto; José Marona; Tiago Costa; Walter Castelão; Ana Bento Silva; Inês Silva; Maria Helena Lourenço; Margarida Mateus; Nuno Pina Gonçalves; Santiago Manica; Manuela Costa; Fernando M Pimentel-Santos; Ana Filipa Mourão; Jaime C Branco; Helena Soares
Journal:  Commun Biol       Date:  2021-09-27
  1 in total

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