Literature DB >> 24553601

Fluorescent probes for detecting monoamine oxidase activity and cell imaging.

Xuefeng Li1, Huatang Zhang, Yusheng Xie, Yi Hu, Hongyan Sun, Qing Zhu.   

Abstract

A series of new fluorogenic probes for monoamine oxidases (MAOs) were reported based on an oxidation and β-elimination mechanism. The limits of detection of the probes for MAO-A and -B were determined to be 3.5 and 6.0 μg mL(-1) respectively. These probes displayed strong activity towards MAOs, especially MAO-B. Cellular imaging studies were also successfully conducted with MCF-7 cells.

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Year:  2014        PMID： 24553601     DOI： 10.1039/c3ob42326c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

Review 1.  Kinetics, mechanism, and inhibition of monoamine oxidase.

Authors:  Rona R Ramsay; Alen Albreht
Journal:  J Neural Transm (Vienna)       Date:  2018-03-07       Impact factor: 3.575

Review 2.  Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives.

Authors:  Qiang Jin; JingJing Wu; Yue Wu; Hongxin Li; Moshe Finel; Dandan Wang; Guangbo Ge
Journal:  Acta Pharm Sin B       Date:  2022-01-21       Impact factor: 14.903

3.  Red emission fluorescent probes for visualization of monoamine oxidase in living cells.

Authors:  Ling-Ling Li; Kun Li; Yan-Hong Liu; Hao-Ran Xu; Xiao-Qi Yu
Journal:  Sci Rep       Date:  2016-08-08       Impact factor: 4.379

4.  Optical molecular imaging of lysyl oxidase activity - detection of active fibrogenesis in human lung tissue.

Authors:  Tashfeen Aslam; Amy Miele; Sunay V Chankeshwara; Alicia Megia-Fernandez; Chesney Michels; Ahsan R Akram; Neil McDonald; Nik Hirani; Chris Haslett; Mark Bradley; Kevin Dhaliwal
Journal:  Chem Sci       Date:  2015-06-08       Impact factor: 9.825
  4 in total

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