Literature DB >> 2455271

A voltage-dependent calcium current in mouse Swiss 3T3 fibroblasts.

A Peres1, R Zippel, E Sturani, G Mostacciuolo.   

Abstract

Patch-clamp experiments in the whole-cell mode have been performed in Swiss 3T3 mouse fibroblasts. Depolarizations from negative holding potential (Vh less than -60 mV) gave rise to a rapidly activating, fully inactivating, inward current of few tenths of nA in physiological saline at 35 degrees C. The current persisted when external Na+ was replaced by impermeant TMA+ and disappeared in 0 Ca2+, 1 mM EGTA. The current was reversible blocked by Co2+ and it was slightly reduced when external Ca2+ was substituted by Ba2+. Finally its reversal potential changed with Nernstian slope with increasing external Ca2+ concentrations. It is concluded that these cells possess a voltage-dependent Ca2+ channel.

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Year:  1988        PMID： 2455271     DOI： 10.1007/bf00582377

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  25 in total

1.  Oscillations of membrane potential in L cells. I. Basic characteristics.

Authors:  Y Okada; Y Doida; G Roy; W Tsuchiya; K Inouye; A Inouye
Journal:  J Membr Biol       Date:  1977-08-04       Impact factor: 1.843

2.  The calcium current of mouse egg measured in physiological calcium and temperature conditions.

Authors:  A Peres
Journal:  J Physiol       Date:  1987-10       Impact factor: 5.182

3.  A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurones.

Authors:  E Carbone; H D Lux
Journal:  Nature       Date:  1984 Aug 9-15       Impact factor: 49.962

4.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

5.  Periodic hyperpolarizing responses in hamster and mouse eggs fertilized with mouse sperm.

Authors:  Y Igusa; S Miyazaki; N Yamashita
Journal:  J Physiol       Date:  1983-07       Impact factor: 5.182

6.  Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.

Authors:  B Ek; C H Heldin
Journal:  J Biol Chem       Date:  1982-09-10       Impact factor: 5.157

Review 7.  Inositol phosphates turnover, cytosolic Ca++ and pH: putative signals for the control of cell growth.

Authors:  L M Vicentini; M L Villereal
Journal:  Life Sci       Date:  1986-06-23       Impact factor: 5.037

8.  Membrane voltage, resistance, and channel switching in isolated mouse fibroblasts (L cells): a patch-electrode analysis.

Authors:  S Hosoi; C L Slayman
Journal:  J Physiol       Date:  1985-10       Impact factor: 5.182

9.  EGF raises cytosolic Ca2+ in A431 and Swiss 3T3 cells by a dual mechanism. Redistribution from intracellular stores and stimulated influx.

Authors:  A Pandiella; A Malgaroli; J Meldolesi; L M Vicentini
Journal:  Exp Cell Res       Date:  1987-05       Impact factor: 3.905

10.  Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH.

Authors:  S A Mendoza; J A Schneider; A Lopez-Rivas; J W Sinnett-Smith; E Rozengurt
Journal:  J Cell Biol       Date:  1986-06       Impact factor: 10.539
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  2 in total

1.  Potassium and calcium currents and action potentials in mouse Balb/c 3T3 fibroblasts.

Authors:  D Lovisolo; G Alloatti; G Bonelli; L Tessitore; F M Baccino
Journal:  Pflugers Arch       Date:  1988-10       Impact factor: 3.657

2.  Electrophysiological and immunohistochemical analysis of muscle differentiation in a mouse mesodermal stem cell line.

Authors:  Y Kubo
Journal:  J Physiol       Date:  1991-10       Impact factor: 5.182
  2 in total

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