Literature DB >> 24552296

Copper(I)-catalyzed aryl or vinyl addition to electron-deficient alkenes cascaded by cationic cyclization.

Bing Zhou1, Wei Hou, Yaxi Yang, Huijin Feng, Yuanchao Li.   

Abstract

An exoselective copper-catalyzed arylation- and vinylation-carbocyclization of electron-deficient alkenes was developed to provide rapid and efficient access to a variety of functionalized 3,3-disubstituted oxindoles. With this method, a highly efficient and concise formal synthesis of (±)-physostigmine and (±)-physovenine has been completed.

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Year:  2014        PMID: 24552296     DOI: 10.1021/ol500033w

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Pardon the Interruption: A Modification of Fischer's Venerable Reaction for the Synthesis of Heterocycles and Natural Products.

Authors:  Robert B Susick; Lucas A Morrill; Elias Picazo; Neil K Garg
Journal:  Synlett       Date:  2017       Impact factor: 2.454

2.  Synthesis of fluoro-functionalized diaryl-λ3-iodonium salts and their cytotoxicity against human lymphoma U937 cells.

Authors:  Prajwalita Das; Etsuko Tokunaga; Norio Shibata; Hidehiko Akiyama; Hiroki Doi; Norimichi Saito
Journal:  Beilstein J Org Chem       Date:  2018-02-07       Impact factor: 2.883

  2 in total

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