Literature DB >> 24552251

Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity.

Kevin S Chu1, Mathew C Finniss, Allison N Schorzman, Jennifer L Kuijer, J Christopher Luft, Charles J Bowerman, Mary E Napier, Zishan A Haroon, William C Zamboni, Joseph M DeSimone.   

Abstract

Delivery systems designed to have triggered release after passively targeting the tumor may improve small molecule chemotherapeutic delivery. Particle replication in nonwetting templates was used to prepare nanoparticles to passively target solid tumors in an A549 subcutaneous xenograft model. An acid labile prodrug was delivered to minimize systemic free docetaxel concentrations and improve tolerability without compromising efficacy.

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Year:  2014        PMID： 24552251      PMCID： PMC4157645          DOI： 10.1021/nl4046558

Source DB:  PubMed          Journal:  Nano Lett        ISSN： 1530-6984            Impact factor:   11.189


  21 in total

1.  Development of docetaxel-loaded intravenous formulation, Nanoxel-PM™ using polymer-based delivery system.

Authors:  Sa-Won Lee; Min-Hyuk Yun; Seung Wei Jeong; Chang-Hoon In; Ji-Young Kim; Min-Hyo Seo; Chaul-Min Pai; Sun-Ok Kim
Journal:  J Control Release       Date:  2011-06-24       Impact factor: 9.776

2.  Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer.

Authors:  William J Gradishar; Sergei Tjulandin; Neville Davidson; Heather Shaw; Neil Desai; Paul Bhar; Michael Hawkins; Joyce O'Shaughnessy
Journal:  J Clin Oncol       Date:  2005-09-19       Impact factor: 44.544

3.  Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor-bearing mice.

Authors:  Thomas Schluep; Jianjun Cheng; Kay T Khin; Mark E Davis
Journal:  Cancer Chemother Pharmacol       Date:  2005-08-26       Impact factor: 3.333

4.  Biodistribution of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in mice with ovarian OCa-1 tumor.

Authors:  C Li; R A Newman; Q P Wu; S Ke; W Chen; T Hutto; Z Kan; M D Brannan; C Charnsangavej; S Wallace
Journal:  Cancer Chemother Pharmacol       Date:  2000       Impact factor: 3.333

5.  HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.

Authors:  Tomás Etrych; Milada Sírová; L Starovoytova; Blanka Ríhová; Karel Ulbrich
Journal:  Mol Pharm       Date:  2010-08-02       Impact factor: 4.939

6.  DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies.

Authors:  Florence Meyer-Losic; Céline Nicolazzi; Jérôme Quinonero; Fabien Ribes; Matthieu Michel; Vincent Dubois; Catherine de Coupade; Matthieu Boukaissi; Anne-Sophie Chéné; Isabelle Tranchant; Valérie Arranz; Imane Zoubaa; Jean-Sébastien Fruchart; Denis Ravel; Jonathan Kearsey
Journal:  Clin Cancer Res       Date:  2008-04-01       Impact factor: 12.531

7.  Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy.

Authors:  Kevin S Chu; Allison N Schorzman; Mathew C Finniss; Charles J Bowerman; Lei Peng; James C Luft; Andrew J Madden; Andrew Z Wang; William C Zamboni; Joseph M DeSimone
Journal:  Biomaterials       Date:  2013-07-27       Impact factor: 12.479

8.  Enhancement of docetaxel solubility via conjugation of formulation-compatible moieties.

Authors:  Loan Huynh; Jean-Christophe Leroux; Christine Allen
Journal:  Org Biomol Chem       Date:  2009-07-02       Impact factor: 3.876

9.  Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers.

Authors:  Hong Zhao; Belen Rubio; Puja Sapra; Dechun Wu; Prasanna Reddy; Prakash Sai; Anthony Martinez; Ying Gao; Yoany Lozanguiez; Clifford Longley; Lee M Greenberger; Ivan D Horak
Journal:  Bioconjug Chem       Date:  2008-03-28       Impact factor: 4.774

Review 10.  Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer-drug conjugate.

Authors:  Stewart D Chipman; Fred B Oldham; Gabriella Pezzoni; Jack W Singer
Journal:  Int J Nanomedicine       Date:  2006
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  10 in total

1.  An automated multidimensional thin film stretching device for the generation of anisotropic polymeric micro- and nanoparticles.

Authors:  Randall A Meyer; Randall S Meyer; Jordan J Green
Journal:  J Biomed Mater Res A       Date:  2015-02-24       Impact factor: 4.396

2.  Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

Authors:  Robert J Sharpe; Justin T Malinowski; Federico Sorana; J Christopher Luft; Charles J Bowerman; Joseph M DeSimone; Jeffrey S Johnson
Journal:  Bioorg Med Chem       Date:  2015-02-21       Impact factor: 3.641

3.  Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation.

Authors:  Kevin G Reuter; Jillian L Perry; Dongwook Kim; J Christopher Luft; Rihe Liu; Joseph M DeSimone
Journal:  Nano Lett       Date:  2015-09-30       Impact factor: 11.189

4.  Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

Authors:  Charles J Bowerman; James D Byrne; Kevin S Chu; Allison N Schorzman; Amanda W Keeler; Candice A Sherwood; Jillian L Perry; James C Luft; David B Darr; Allison M Deal; Mary E Napier; William C Zamboni; Norman E Sharpless; Charles M Perou; Joseph M DeSimone
Journal:  Nano Lett       Date:  2016-12-22       Impact factor: 11.189

5.  Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases.

Authors:  Maria Sambade; Allison Deal; Allison Schorzman; J Christopher Luft; Charles Bowerman; Kevin Chu; Olga Karginova; Amanda Van Swearingen; William Zamboni; Joseph DeSimone; Carey K Anders
Journal:  Nanomedicine (Lond)       Date:  2016-07-26       Impact factor: 5.307

Review 6.  Biomimetic particles as therapeutics.

Authors:  Randall A Meyer; Joel C Sunshine; Jordan J Green
Journal:  Trends Biotechnol       Date:  2015-08-12       Impact factor: 19.536

Review 7.  Shaping the future of nanomedicine: anisotropy in polymeric nanoparticle design.

Authors:  Randall A Meyer; Jordan J Green
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2015-05-15

8.  Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells.

Authors:  Yashdeep Phanse; Brendan M Dunphy; Jillian L Perry; Paul M Airs; Cynthia C H Paquette; Jonathan O Carlson; Jing Xu; J Christopher Luft; Joseph M DeSimone; Barry J Beaty; Lyric C Bartholomay
Journal:  PLoS Negl Trop Dis       Date:  2015-05-21

9.  Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation.

Authors:  Randall A Meyer; Mohit P Mathew; Elana Ben-Akiva; Joel C Sunshine; Ron B Shmueli; Qiuyin Ren; Kevin J Yarema; Jordan J Green
Journal:  Acta Biomater       Date:  2018-04-07       Impact factor: 8.947

10.  Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP.

Authors:  Angela X Gao; Longyan Liao; Jeremiah A Johnson
Journal:  ACS Macro Lett       Date:  2014-08-13       Impact factor: 6.903
  10 in total

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