Literature DB >> 24551729

Assessment of blood glucose using gingival crevicular blood in diabetic and non-diabetic patients: a chair side method.

Harmanpreet Kaur1, Bhawanpreet Singh2, Anshu Sharma3.   

Abstract

AIM: Diabetes mellitus is undiagnosed in approximately half of the patients actually suffering from the disease. The prevalence of diabetes mellitus is nearly twice in patients with periodontitis as compared to periodontally healthy subjects.In addition, the prevalence of Diabetes mellitus is more than twice as high as in patients with periodontitis when compared to periodontally healthy subjects. The purpose of the present study was to evaluate whether blood oozing from gingival crevice during routine periodontal examination can be used for determining glucose levels.
MATERIAL AND METHODS: In the present study 50 patients(25 diabetic and 25 non-diabetic) with chronic periodontitis were selected and were divided into two groups i.e. Group I and Group II, respectively. Blood glucose measurements were made using gingival crevicular blood, finger stick blood using glucose self-monitoring device (Finetest(TM); Infopia Co.Ltd;Korea) and at the same time intra venous blood was collected for measurement in a laboratory glucose analyzer. Each laboratory measurement was corrected from a serum glucose value to a whole blood glucose value by a function of the patient's haematocrit.
RESULTS: The patient's blood glucose values ranged from 83.6 to 483mg/dl in diabetic patients(Group I) and 70-218 mg/dl in non-diabetic individuals (Group II) to 83.6 to 483mg/dl. The comparison between gingival crevicular blood, finger-prick blood and corrected intra venous blood showed a very strong correlation with an r value of 0.99(P level< 0.001)
CONCLUSION: The data from this study has shown that gingival crevicular blood collected during diagnostic periodontal examination can be an excellent source of blood for glucometric analysis.

Entities:  

Keywords:  Chronic periodontitis; Corrected intravenous blood; Diabetes mellitus; Finger prick blood; Gingival crevicular blood

Year:  2013        PMID: 24551729      PMCID: PMC3919341          DOI: 10.7860/JCDR/2013/7705.3854

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  13 in total

1.  Transdermal monitoring of glucose and other analytes using ultrasound.

Authors:  J Kost; S Mitragotri; R A Gabbay; M Pishko; R Langer
Journal:  Nat Med       Date:  2000-03       Impact factor: 53.440

Review 2.  Periodontal management of the patient with diabetes mellitus.

Authors:  T D Rees
Journal:  Periodontol 2000       Date:  2000-06       Impact factor: 7.589

Review 3.  Early detection of undiagnosed diabetes mellitus: a US perspective.

Authors:  M I Harris; R C Eastman
Journal:  Diabetes Metab Res Rev       Date:  2000 Jul-Aug       Impact factor: 4.876

Review 4.  Noninvasive blood glucose monitoring.

Authors:  D C Klonoff
Journal:  Diabetes Care       Date:  1997-03       Impact factor: 19.112

5.  Reliability of intraoral blood for diabetes screening.

Authors:  P Tsutsui; S K Rich; S E Schonfeld
Journal:  J Oral Med       Date:  1985 Apr-Jun

Review 6.  Epidemiology of diabetes in India--three decades of research.

Authors:  A Ramachandran
Journal:  J Assoc Physicians India       Date:  2005-01

7.  In-dental-office screening for diabetes mellitus using gingival crevicular blood.

Authors:  T Beikler; A Kuczek; G Petersilka; T F Flemmig
Journal:  J Clin Periodontol       Date:  2002-03       Impact factor: 8.728

Review 8.  Periodontal disease and diabetes mellitus: a two-way relationship.

Authors:  S G Grossi; R J Genco
Journal:  Ann Periodontol       Date:  1998-07

9.  Gingival crevicular blood for assessment of blood glucose in diabetic patients.

Authors:  R C Parker; J W Rapley; W Isley; P Spencer; W J Killoy
Journal:  J Periodontol       Date:  1993-07       Impact factor: 6.993

10.  Relation between control of diabetes and gingival bleeding.

Authors:  T Ervasti; M Knuuttila; L Pohjamo; K Haukipuro
Journal:  J Periodontol       Date:  1985-03       Impact factor: 6.993

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  2 in total

Review 1.  Saliva-based biosensors: noninvasive monitoring tool for clinical diagnostics.

Authors:  Radha S P Malon; Sahba Sadir; Malarvili Balakrishnan; Emma P Córcoles
Journal:  Biomed Res Int       Date:  2014-09-08       Impact factor: 3.411

2.  Correlations between gingival crevicular blood glucose and capillary blood glucose: A preliminary report.

Authors:  Siluvai Sibyl; Darshana Bennadi; Nandita Kshetrimayum; Maurya Manjunath
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  2 in total

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