Literature DB >> 24551651

Echocardiography guided therapy for myocarditis after scorpion sting envenomation.

Suresh V Sagarad1, Sudha Biradar Kerure2, Balaramsingh Thakur3, S S Reddy4, Balasubramanya K5, R M Joshi6.   

Abstract

OBJECTIVE: This study was to evaluate echocardiographic findings and its usefulness in clinical management of patients with scorpion sting envenomation.
MATERIAL AND METHODS: A total of 84 consecutive patients were prospectively studied. The data included demographics, at the time of presentation to the hospital, the clinical features, echocardiographic findings, admission to intensive care unit, use of inotropic medication, time to discharge, and mortality.
RESULTS: Out of 84 patients studied 60 patients (71.4%) had echocardiographic evidence of myocarditis (LVEF <50%). Majority of patients had LVEF <40% (50 patients, 83.3%). Severe LV dysfunction (LVEF <30%) was noted in 20 patients (33.3%). No patient had significant valvular regurgitation. RV dysfunction was noted in half of the patients who had LV dysfunction. RV dysfunction was not seen in isolation. Twenty four patients without evidence of myocarditis on echocardiography were observed in general wards and were discharged in 24 to 48 hours of admission. Ten patients with mild LV dysfunction (LVEF 50-40%) and 20 patients with moderate LV dysfunction were observed in high dependency units with regular monitoring for 24 to 48 hours. Only 3 patients were put on inotropics support and others could be discharged in 72 to 96 hours. All the patients with severe LV dysfunction and moderate LV dysfunction with significant RV dysfunction were admitted in intensive care unit irrespective of symptoms (Total 30 patients). These patients were put on inotropics support. Among severe LV dysfunction group, 4 patients required ventilator support and 2 (2.3%) patients died with refractory shock and multi-organ failure. Tachycardia, muffled and or gallop heart sounds and hypertension didn't predict presence of LV dysfunction. Persistent hypotension requiring inotropics support was a marker of severe LV dysfunction.
CONCLUSION: Echocardiography is a useful tool in emergency to assess LV function in patients with scorpion sting envenomation. It can guide therapy by identifying patients with severe LV dysfunction.

Entities:  

Keywords:  Echocardiography; Envenomation; Myocarditis; Scorpion

Year:  2013        PMID: 24551651      PMCID: PMC3919280          DOI: 10.7860/JCDR/2013/6791.3693

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  24 in total

1.  Scorpion envenomation among children: clinical manifestations and outcome (analysis of 685 cases).

Authors:  Mabrouk Bahloul; Imen Chabchoub; Anis Chaari; Kamilia Chtara; Hatem Kallel; Hassen Dammak; Hichem Ksibi; Hedi Chelly; Noureddine Rekik; Chokri Ben Hamida; Mounir Bouaziz
Journal:  Am J Trop Med Hyg       Date:  2010-11       Impact factor: 2.345

2.  Electrocardiographic, enzymatic and echocardiographic evidence of myocardial damage after Tityus serrulatus scorpion poisoning.

Authors:  C F Amaral; J A Lopes; R A Magalhães; N A de Rezende
Journal:  Am J Cardiol       Date:  1991-03-15       Impact factor: 2.778

3.  Echocardiographic and radionuclide angiographic observations following scorpion envenomation by Leiurus quinquestriatus.

Authors:  M Gueron; G Margulis; S Sofer
Journal:  Toxicon       Date:  1990       Impact factor: 3.033

4.  Consecutive stings by red scorpions evoke severe cardiovascular manifestations in the first, but not in the second, victim: a clinical observation.

Authors:  H S Bawaskar; P H Bawaskar
Journal:  J Trop Med Hyg       Date:  1991-08

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Authors:  M Gueron; R Yaron
Journal:  Chest       Date:  1970-02       Impact factor: 9.410

6.  Myocardial injury without heart failure following envenomation by the scorpion Leiurus quinquestriatus in children.

Authors:  S Sofer; E Shahak; A Slonim; M Gueron
Journal:  Toxicon       Date:  1991       Impact factor: 3.033

7.  Direct vs. mediated effects of scorpion venom: an experimental study of the effects of a second challenge with scorpion venom.

Authors:  Lamia Ouanes-Besbes; Souhail El Atrous; Semir Nouira; Nicolas Aubrey; Alain Carayon; Mohamed El Ayeb; Fekri Abroug
Journal:  Intensive Care Med       Date:  2005-01-28       Impact factor: 17.440

8.  Scorpion sting envenomation in children in southeast Turkey.

Authors:  Mehmet Bosnak; Aydin Ece; Ilyas Yolbas; Vuslat Bosnak; Metin Kaplan; Fuat Gurkan
Journal:  Wilderness Environ Med       Date:  2009       Impact factor: 1.518

9.  Vasodilators and hypertensive encephalopathy following scorpion envenomation in children.

Authors:  S Sofer; M Gueron
Journal:  Chest       Date:  1990-01       Impact factor: 9.410

10.  Significance of assessment of serum cardiac troponin I and interleukin-8 in scorpion envenomed children.

Authors:  Abdel-Raheem A M Meki; Zeinab M M Mohamed; Hasan M Mohey El-deen
Journal:  Toxicon       Date:  2003-02       Impact factor: 3.033

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