Literature DB >> 24551400

Temporal abstraction-based clinical phenotyping with Eureka!

Andrew R Post1, Tahsin Kurc1, Richie Willard1, Himanshu Rathod1, Michel Mansour1, Akshatha Kalsanka Pai1, William M Torian1, Sanjay Agravat1, Suzanne Sturm1, Joel H Saltz1.   

Abstract

Temporal abstraction, a method for specifying and detecting temporal patterns in clinical databases, is very expressive and performs well, but it is difficult for clinical investigators and data analysts to understand. Such patterns are critical in phenotyping patients using their medical records in research and quality improvement. We have previously developed the Analytic Information Warehouse (AIW), which computes such phenotypes using temporal abstraction but requires software engineers to use. We have extended the AIW's web user interface, Eureka! Clinical Analytics, to support specifying phenotypes using an alternative model that we developed with clinical stakeholders. The software converts phenotypes from this model to that of temporal abstraction prior to data processing. The model can represent all phenotypes in a quality improvement project and a growing set of phenotypes in a multi-site research study. Phenotyping that is accessible to investigators and IT personnel may enable its broader adoption.

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Year:  2013        PMID: 24551400      PMCID: PMC3900137     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  12 in total

1.  Visually defining and querying consistent multi-granular clinical temporal abstractions.

Authors:  Carlo Combi; Barbara Oliboni
Journal:  Artif Intell Med       Date:  2011-12-15       Impact factor: 5.326

2.  Analyzing the heterogeneity and complexity of Electronic Health Record oriented phenotyping algorithms.

Authors:  Mike Conway; Richard L Berg; David Carrell; Joshua C Denny; Abel N Kho; Iftikhar J Kullo; James G Linneman; Jennifer A Pacheco; Peggy Peissig; Luke Rasmussen; Noah Weston; Christopher G Chute; Jyotishman Pathak
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

3.  Implementation of the federal health information technology initiative.

Authors:  David Blumenthal
Journal:  N Engl J Med       Date:  2011-12-22       Impact factor: 91.245

4.  Wiring the health system--origins and provisions of a new federal program.

Authors:  David Blumenthal
Journal:  N Engl J Med       Date:  2011-12-15       Impact factor: 91.245

Review 5.  Temporal abstraction in intelligent clinical data analysis: a survey.

Authors:  Michael Stacey; Carolyn McGregor
Journal:  Artif Intell Med       Date:  2006-09-29       Impact factor: 5.326

6.  Searching electronic health records for temporal patterns in patient histories: a case study with microsoft amalga.

Authors:  Catherine Plaisant; Stanley Lam; Stanley J Lam; Ben Shneiderman; Mark S Smith; David Roseman; David H Roseman; Greg Marchand; Michael Gillam; Craig Feied; Jonathan Handler; Hank Rappaport
Journal:  AMIA Annu Symp Proc       Date:  2008-11-06

7.  The Analytic Information Warehouse (AIW): a platform for analytics using electronic health record data.

Authors:  Andrew R Post; Tahsin Kurc; Sharath Cholleti; Jingjing Gao; Xia Lin; William Bornstein; Dedra Cantrell; David Levine; Sam Hohmann; Joel H Saltz
Journal:  J Biomed Inform       Date:  2013-02-09       Impact factor: 6.317

8.  Leveraging derived data elements in data analytic models for understanding and predicting hospital readmissions.

Authors:  Sharath Cholleti; Andrew Post; Jingjing Gao; Xia Lin; William Bornstein; Dedra Cantrell; Joel Saltz
Journal:  AMIA Annu Symp Proc       Date:  2012-11-03

9.  PROTEMPA: a method for specifying and identifying temporal sequences in retrospective data for patient selection.

Authors:  Andrew R Post; James H Harrison
Journal:  J Am Med Inform Assoc       Date:  2007-06-28       Impact factor: 4.497

10.  A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research.

Authors:  Andrew Post; Tahsin Kurc; Marc Overcash; Dedra Cantrell; Tim Morris; Kristi Eckerson; Circe Tsui; Terry Willey; Arshed Quyyumi; Danny Eapen; Guillermo Umpierrez; David Ziemer; Joel Saltz
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2011-03-07
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  4 in total

1.  Learning Optimal Individualized Treatment Rules from Electronic Health Record Data.

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Journal:  IEEE Int Conf Healthc Inform       Date:  2016-12-08

2.  Development of an automated phenotyping algorithm for hepatorenal syndrome.

Authors:  Jejo D Koola; Sharon E Davis; Omar Al-Nimri; Sharidan K Parr; Daniel Fabbri; Bradley A Malin; Samuel B Ho; Michael E Matheny
Journal:  J Biomed Inform       Date:  2018-03-09       Impact factor: 6.317

3.  I2b2-etl: Python application for importing electronic health data into the informatics for integrating biology and the bedside platform.

Authors:  Kavishwar B Wagholikar; Layne Ainsworth; David Zelle; Kira Chaney; Michael Mendis; Jeffery Klann; Alexander J Blood; Angela Miller; Rupendra Chulyadyo; Michael Oates; William J Gordon; Samuel J Aronson; Benjamin M Scirica; Shawn N Murphy
Journal:  Bioinformatics       Date:  2022-10-14       Impact factor: 6.931

4.  A Modular Architecture for Electronic Health Record-Driven Phenotyping.

Authors:  Luke V Rasmussen; Richard C Kiefer; Huan Mo; Peter Speltz; William K Thompson; Guoqian Jiang; Jennifer A Pacheco; Jie Xu; Qian Zhu; Joshua C Denny; Enid Montague; Jyotishman Pathak
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2015-03-25
  4 in total

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