Literature DB >> 24549854

Bowel dysfunction in spinal cord injury: current perspectives.

Yuehai Pan1, Bin Liu, Ruijun Li, Zhixin Zhang, Laijin Lu.   

Abstract

Permanent disruptions of gastrointestinal function are very common sequel of spinal cord injury (SCI). When motor and sensory nervous integrity are severely affected, neurogenic gastrointestinal dysfunction is an inevitable consequence. Autonomic nervous system miss function has significantly diminished or lost sensory sensations followed with incomplete evacuation of stool from the rectal vault, immobility, and reduced anal sphincter tone all of those predisposing to increased risk of fecal incontinence (FI). The FI is, beside paralysis of extremities, one of the symptoms most profoundly affecting quality of life (QOL) in patients with SCI. We are reviewing current perspectives in management of SCI, discussing some pathophysiology mechanisms which could be addressed and pointing toward actual practical concepts in use for evaluation and improvements necessary to sustain SCI patients QOL.

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Year:  2014        PMID: 24549854     DOI: 10.1007/s12013-014-9842-6

Source DB:  PubMed          Journal:  Cell Biochem Biophys        ISSN: 1085-9195            Impact factor:   2.194


  11 in total

1.  Risk factors for the development of osteoporosis after spinal cord injury. A 12-month follow-up study.

Authors:  L Gifre; J Vidal; J L Carrasco; A Muxi; E Portell; A Monegal; N Guañabens; P Peris
Journal:  Osteoporos Int       Date:  2015-05-05       Impact factor: 4.507

2.  Anatomical and Functional Changes to the Colonic Neuromuscular Compartment after Experimental Spinal Cord Injury.

Authors:  Amanda R White; Gregory M Holmes
Journal:  J Neurotrauma       Date:  2018-02-09       Impact factor: 5.269

3.  Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia.

Authors:  Scott A Myers; Leila Gobejishvili; Sujata Saraswat Ohri; C Garrett Wilson; Kariena R Andres; Amberly S Riegler; Hridgandh Donde; Swati Joshi-Barve; Shirish Barve; Scott R Whittemore
Journal:  Neurobiol Dis       Date:  2018-12-14       Impact factor: 5.996

Review 4.  Bowel Dysfunction in Spinal Cord Injury.

Authors:  Zhengyan Qi; James W Middleton; Allison Malcolm
Journal:  Curr Gastroenterol Rep       Date:  2018-08-29

Review 5.  Bowel dysfunction after elective spinal surgery: etiology, diagnostics and management based on the medical literature and experience in a university hospital.

Authors:  A Jaber; S Hemmer; R Klotz; T Ferbert; C Hensel; C Eisner; Y M Ryang; P Obid; K Friedrich; W Pepke; M Akbar
Journal:  Orthopade       Date:  2021-06       Impact factor: 1.087

6.  Novel method for restoration of anorectal function following spinal cord injury via nerve transfer in rats.

Authors:  Bingbo Bao; Kai Fu; Xianyou Zheng; Haifeng Wei; Pengbo Luo; Hongyi Zhu; Xiaozhong Zhu; Xingwei Li; Tao Gao
Journal:  J Spinal Cord Med       Date:  2018-03-06       Impact factor: 1.985

Review 7.  Colostomy and quality of life after spinal cord injury: systematic review.

Authors:  O Waddell; A McCombie; F Frizelle
Journal:  BJS Open       Date:  2020-08-27

Review 8.  Spinal cord injury - there is not just one way of treating it.

Authors:  Veronica Estrada; Hans Werner Müller
Journal:  F1000Prime Rep       Date:  2014-09-04

Review 9.  Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment.

Authors:  Melissa Schepers; Assia Tiane; Dean Paes; Selien Sanchez; Ben Rombaut; Elisabeth Piccart; Bart P F Rutten; Bert Brône; Niels Hellings; Jos Prickaerts; Tim Vanmierlo
Journal:  Front Immunol       Date:  2019-07-24       Impact factor: 7.561

10.  Promoting Long-Term Health among People with Spinal Cord Injury: What's New?

Authors:  Mary Ann McColl; Shikha Gupta; Karen Smith; Alexander McColl
Journal:  Int J Environ Res Public Health       Date:  2017-12-06       Impact factor: 3.390

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