Literature DB >> 24549832

Significant variation in recommendation of care for women of reproductive age with ulcerative colitis postileal pouch-anal anastomosis.

Kara Bradford1, Gil Y Melmed, Phillip Fleshner, Neil Silverman, Marla C Dubinsky.   

Abstract

BACKGROUND AND AIM: Ileal pouch-anal anastomosis (IPAA) is the preferred surgical option for treatment refractory ulcerative colitis. Infertility risk post IPAA and sphincter injury concerns with vaginal delivery has led to a lack of consensus regarding timing and recommended mode of delivery (MOD) post-IPAA. To better understand these issues, we surveyed gastroenterologists (GI), colorectal surgeons (CRS), and obstetricians (OB) to assess practice variation in recommendations for delivery post IPAA.
METHODS: Clinical vignettes were developed to assess knowledge, attitudes, and beliefs surrounding (1) the impact of IPAA on fertility, (2) IPAA timing around pregnancy, (3) recommended MOD after IPAA and (4) which specialist should advise on MOD. These were emailed to providers using specialty society address lists. Univariate analyses tested differences among groups.
RESULTS: A total of 244 GI, 158 CRS and 39 OBs responded to the survey. The majority of GI (67%) and CRS (60%) quoted fertility reduction of >20% post-IPAA versus 11% OB (p < 0.001). More GI than CRS (67 vs. 45%) recommended delaying IPAA until after pregnancy (p < 0.001), and this was more commonly suggested by CRS in practice <10 years (p = 0.01) and <45 years old (p = 0.003). Vaginal delivery was recommended post-IPAA in 43, 20 and 57% for GI, CRS and OB, respectively (p < 0.001). Only 28% CRS versus 59% OB thought OB should primarily advise on MOD (p < 0.001).
CONCLUSIONS: There is significant intra- and inter-group variation in management of women post-IPAA. There is need for consensus among subspecialists involved in managing women with this complex condition.

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Year:  2014        PMID: 24549832     DOI: 10.1007/s10620-014-3043-4

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  5 in total

1.  Pregnancy, delivery, and pouch function after ileal pouch-anal anastomosis for ulcerative colitis.

Authors:  A Ravid; C S Richard; L M Spencer; B I O'Connor; E D Kennedy; H M MacRae; Z Cohen; R S McLeod
Journal:  Dis Colon Rectum       Date:  2002-10       Impact factor: 4.585

Review 2.  A meta-analysis on the influence of inflammatory bowel disease on pregnancy.

Authors:  J Cornish; E Tan; J Teare; T G Teoh; R Rai; S K Clark; P P Tekkis
Journal:  Gut       Date:  2006-12-21       Impact factor: 23.059

3.  Surgical management of ulcerative colitis: a comparison of Canadian and American colorectal surgeons.

Authors:  Devon Richardson; Sandra deMontbrun; Paul M Johnson
Journal:  Can J Surg       Date:  2011-08       Impact factor: 2.089

4.  Injury to innervation of pelvic floor sphincter musculature in childbirth.

Authors:  S J Snooks; M Setchell; M Swash; M M Henry
Journal:  Lancet       Date:  1984-09-08       Impact factor: 79.321

5.  Female fertility and childbirth after ileal pouch-anal anastomosis for ulcerative colitis.

Authors:  A Lepistö; S Sarna; A Tiitinen; H J Järvinen
Journal:  Br J Surg       Date:  2007-04       Impact factor: 6.939

  5 in total
  7 in total

Review 1.  Implementing quality measures for inflammatory bowel disease.

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2.  Multidisciplinary Team-Based Approaches to IBD Management: How Might "One-Stop Shopping" Work for Complex IBD Care?

Authors:  Chang Kyun Lee; Gil Y Melmed
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3.  Pregnancy concerns in patients with ileal pouch anal anastomosis for ulcerative colitis: time for increased education across specialties.

Authors:  Kim L Isaacs
Journal:  Dig Dis Sci       Date:  2014-06       Impact factor: 3.199

4.  Childbearing and Delivery in Women With Ulcerative Colitis and Ileostomy or Ileal Pouch-Anal Anastomosis.

Authors:  Michele Campigotto; Andrea Braini; Maria Maddalena Casarotto; Saveria Lory Crocè; Renato Sablich
Journal:  ACG Case Rep J       Date:  2022-06-23

5.  Identifying Patient Priorities for Preconception and Pregnancy Counseling in IBD.

Authors:  Aiya Aboubakr; Alexa Rae Riggs; Darwin Jimenez; Maria Teresa Mella; Marla C Dubinsky
Journal:  Dig Dis Sci       Date:  2020-07-20       Impact factor: 3.199

Review 6.  The Impact of Inflammatory Bowel Disease on Pregnancy and the Fetus: A Literature Review.

Authors:  Hira Pervez; Norina Usman; Munis M Ahmed; Mydah S Hashmi
Journal:  Cureus       Date:  2019-09-13

7.  Delivery Mode after Ileal Pouch-Anal Anastomosis among Pregnant Women with Ulcerative Colitis.

Authors:  Yoshiko Goto; Motoi Uchino; Yuki Horio; Kurando Kusunoki; Tomohiro Minagawa; Ryuichi Kuwahara; Kei Kimura; Kozo Kataoka; Naohito Beppu; Masataka Ikeda; Hiroki Ikeuchi
Journal:  J Anus Rectum Colon       Date:  2021-10-28
  7 in total

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