Literature DB >> 24549723

Sensitive periods for hormonal programming of the brain.

Geert J de Vries1, Christopher T Fields, Nicole V Peters, Jack Whylings, Matthew J Paul.   

Abstract

During sensitive periods, information from the external and internal environment that occurs during particular phases of development is relayed to the brain to program neural development. Hormones play a central role in this process. In this review, we first discuss sexual differentiation of the brain as an example of hormonal programming. Using sexual differentiation, we define sensitive periods, review cellular and molecular processes that can explain their restricted temporal window, and discuss challenges in determining the precise timing of the temporal window. We then briefly review programming effects of other hormonal systems and discuss how programming of these systems interact with sexual differentiation.

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Year:  2014        PMID: 24549723     DOI: 10.1007/7854_2014_286

Source DB:  PubMed          Journal:  Curr Top Behav Neurosci        ISSN: 1866-3370


  10 in total

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8.  Sex differences in auditory brainstem response audiograms from vasopressin-deficient Brattleboro and wild-type Long-Evans rats.

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Journal:  PLoS One       Date:  2019-08-30       Impact factor: 3.240

Review 9.  Sex-specific aging in animals: Perspective and future directions.

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Journal:  Aging Cell       Date:  2022-01-23       Impact factor: 9.304

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  10 in total

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