| Literature DB >> 24548754 |
Abstract
Androgenic alopecia, a condition characterized by increased levels of DHT could have been selected for due to the benefits that prostaglandin D2 (PGD(2)) has on the prostate. A DHT metabolite can increase the transcription of prostaglandin D2 synthase through estrogen receptor beta. The increase of PGD(2) can decrease the risk of prostate cancer and proliferation of prostate cancer cells. Therefore, the mechanisms behind male pattern baldness may also curtail the advancement of prostate cancer.Entities:
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Year: 2014 PMID： 24548754 DOI： 10.1016/j.mehy.2014.01.016
Source DB: PubMed Journal: Med Hypotheses ISSN： 0306-9877 Impact factor: 1.538