Literature DB >> 2454105

Myelin basic protein binds GTP at a single site in the N-terminus.

C K Chan1, J Ramwani, M A Moscarello, K C Chan, J Ranwani.   

Abstract

Myelin basic protein from normal human brain was ADP-ribosylated with Cholera toxin, but not with Pertussis toxin. It bound azido-GTP at a single site in the N-terminal tetrapeptide at the Gln residue. The binding was considerably reduced when GppNHp was present during azido-GTP binding and totally inhibited when GTP gamma S was present. The relevance of this specific binding is not understood at this time.

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Year:  1988        PMID: 2454105     DOI: 10.1016/s0006-291x(88)80451-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  7 in total

1.  Characterization of guanylyl cyclase in purified myelin.

Authors:  M Grabow; G Chakraborty; R W Ledeen
Journal:  Neurochem Res       Date:  1996-04       Impact factor: 3.996

2.  ADP-ribosyltransferase activity in myelin membranes isolated from human brain.

Authors:  C Boulias; F G Mastronardi; M A Moscarello
Journal:  Neurochem Res       Date:  1995-11       Impact factor: 3.996

Review 3.  Analogous structural motifs in myelin basic protein and in MARCKS.

Authors:  G Harauz; N Ishiyama; I R Bates
Journal:  Mol Cell Biochem       Date:  2000-06       Impact factor: 3.396

4.  Myelin basic protein and myelin basic protein peptides induce the proliferation of Schwann cells via ganglioside GM1 and the FGF receptor.

Authors:  S F Tzeng; G E Deibler; G H DeVries
Journal:  Neurochem Res       Date:  1999-02       Impact factor: 3.996

5.  Post-translational modifications of chicken myelin basic protein charge components.

Authors:  Jeongkwon Kim; Rui Zhang; Eric F Strittmatter; Richard D Smith; Robert Zand
Journal:  Neurochem Res       Date:  2008-07-10       Impact factor: 3.996

6.  The structural complexities of the myelin basic protein gene from mouse are also present in shark.

Authors:  R A Saavedra; A Lipson; K S Kimbro; C Ljubetic
Journal:  J Mol Neurosci       Date:  1993       Impact factor: 3.444

7.  Charge isomers of myelin basic protein: structure and interactions with membranes, nucleotide analogues, and calmodulin.

Authors:  Chaozhan Wang; Ute Neugebauer; Jochen Bürck; Matti Myllykoski; Peter Baumgärtel; Jürgen Popp; Petri Kursula
Journal:  PLoS One       Date:  2011-05-25       Impact factor: 3.240

  7 in total

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