Literature DB >> 2454065

Pathogenicity of antigenic variants of Newcastle disease virus Italian strain selected with monoclonal antibodies.

G Meulemans1, M Gonze, M C Carlier, P Petit, A Burny, L E Long.   

Abstract

Antigenic variants of the Italian strain of NDV were selected using monoclonal antibodies directed against the HN and F proteins of Italian virus. Antigenic mapping of the HN and F proteins using variant viruses in cross neutralization tests revealed the presence of at least two different epitopes on HN and four epitopes on F protein. Immunoselected variant viruses were demonstrated to have different intravenous pathogenicity index than the parental Italian virus.

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Year:  1987        PMID： 2454065

Source DB:  PubMed          Journal:  Ann Rech Vet        ISSN： 0003-4193


  3 in total

1.  Mutations located on both F1 and F2 subunits of the Newcastle disease virus fusion protein confer resistance to neutralization with monoclonal antibodies.

Authors:  C Neyt; J Geliebter; M Slaoui; D Morales; G Meulemans; A Burny
Journal:  J Virol       Date:  1989-02       Impact factor: 5.103

2.  The hemagglutinin-neuraminidase (HN) gene of Newcastle disease virus strain Italien (ndv Italien): comparison with HNs of other strains and expression by a vaccinia recombinant.

Authors:  C D Wemers; S de Henau; C Neyt; D Espion; C Letellier; G Meulemans; A Burny
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574

Review 3.  Virulence during Newcastle Disease Viruses Cross Species Adaptation.

Authors:  Claudio L Afonso
Journal:  Viruses       Date:  2021-01-15       Impact factor: 5.048
  3 in total

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