Increased amniotic acetylcholinesterase activity with a fetus papyraceus and aplasia cutis congenita.

A case of an infant with aplasia cutis congenita, a fetus papyraceus, abnormal maternal serum alpha-fetoprotein (MSAFP), elevated amniotic alpha-fetoprotein, and positive amniotic acetylcholinesterase activity represents an uncommon abnormality. Such a case came to our attention as a result of MSAFP screening. The delivery of a neurologically intact infant in the presence of amniotic acetylcholinesterase activity is described.