Literature DB >> 24535546

Emerging role of extracellular vesicles in inflammatory diseases.

Edit I Buzas1, Bence György1, György Nagy2, András Falus1, Steffen Gay3.   

Abstract

The discovery that submicron-sized extracellular vesicles (EVs) are generated by both prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical sciences, and could pave the way for new strategies to combat various diseases. EVs are carriers of pathogen-associated and damage-associated molecular patterns, cytokines, autoantigens and tissue-degrading enzymes. In addition to a possible role in the pathogenesis of a number of inflammatory conditions, such as infections and autoimmune diseases, EVs, including microvesicles (also known as microparticles), exosomes and apoptotic vesicles, have therapeutic potential and might be used as biomarkers for inflammatory diseases. Therefore, molecular diagnostics and targeted therapy could benefit from expanding knowledge in the field. In this Review, we summarize important developments and propose that extracellular vesicles could be used as therapeutic vehicles and as targets for the treatment and prevention of inflammatory diseases.

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Year:  2014        PMID： 24535546     DOI： 10.1038/nrrheum.2014.19

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  116 in total

1.  Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice.

Authors:  Lilla Turiák; Petra Misják; Tamás G Szabó; Borbála Aradi; Krisztina Pálóczi; Oliver Ozohanics; László Drahos; Agnes Kittel; András Falus; Edit I Buzás; Károly Vékey
Journal:  J Proteomics       Date:  2011-05-19       Impact factor: 4.044

2.  Protein targeting to exosomes/microvesicles by plasma membrane anchors.

Authors:  Beiyi Shen; Ning Wu; Jr-Ming Yang; Stephen J Gould
Journal:  J Biol Chem       Date:  2011-02-07       Impact factor: 5.157

3.  Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus.

Authors:  Anirudh J Ullal; Charles F Reich; Megan Clowse; Lisa G Criscione-Schreiber; Martin Tochacek; Marc Monestier; David S Pisetsky
Journal:  J Autoimmun       Date:  2011-03-03       Impact factor: 7.094

Review 4.  Microparticles, vascular function, and atherothrombosis.

Authors:  Pierre-Emmanuel Rautou; Anne-Clémence Vion; Nicolas Amabile; Gilles Chironi; Alain Simon; Alain Tedgui; Chantal M Boulanger
Journal:  Circ Res       Date:  2011-08-19       Impact factor: 17.367

5.  Exosomes derived from interleukin-10-treated dendritic cells can inhibit trinitrobenzene sulfonic acid-induced rat colitis.

Authors:  Xiaojun Yang; Song Meng; Hong Jiang; Tao Chen; Wenxi Wu
Journal:  Scand J Gastroenterol       Date:  2010-10       Impact factor: 2.423

6.  Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke.

Authors:  Chun-Jun Li; Yu Liu; Yan Chen; Demin Yu; Kevin Jon Williams; Ming-Lin Liu
Journal:  Am J Pathol       Date:  2013-03-13       Impact factor: 4.307

7.  Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cells.

Authors:  Anat Aharon; Tal Tamari; Benjamin Brenner
Journal:  Thromb Haemost       Date:  2008-11       Impact factor: 5.249

8.  Unique protein signature of circulating microparticles in systemic lupus erythematosus.

Authors:  Ole Østergaard; Christoffer T Nielsen; Line V Iversen; Julia T Tanassi; Steen Knudsen; Søren Jacobsen; Niels H H Heegaard
Journal:  Arthritis Rheum       Date:  2013-10

9.  ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages.

Authors:  Gizem Ayna; Dmitri V Krysko; Agnieszka Kaczmarek; Goran Petrovski; Peter Vandenabeele; László Fésüs
Journal:  PLoS One       Date:  2012-06-29       Impact factor: 3.240

10.  Standardization of sample collection, isolation and analysis methods in extracellular vesicle research.

Authors:  Kenneth W Witwer; Edit I Buzás; Lynne T Bemis; Adriana Bora; Cecilia Lässer; Jan Lötvall; Esther N Nolte-'t Hoen; Melissa G Piper; Sarada Sivaraman; Johan Skog; Clotilde Théry; Marca H Wauben; Fred Hochberg
Journal:  J Extracell Vesicles       Date:  2013-05-27
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  256 in total

Review 1.  Innate immune cells in the pathogenesis of primary systemic vasculitis.

Authors:  Durga Prasanna Misra; Vikas Agarwal
Journal:  Rheumatol Int       Date:  2015-09-24       Impact factor: 2.631

2.  Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.

Authors:  Joanna Kowal; Guillaume Arras; Marina Colombo; Mabel Jouve; Jakob Paul Morath; Bjarke Primdal-Bengtson; Florent Dingli; Damarys Loew; Mercedes Tkach; Clotilde Théry
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-08       Impact factor: 11.205

3.  Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.

Authors:  Giovanna Leoni; Philipp-Alexander Neumann; Nazila Kamaly; Miguel Quiros; Hikaru Nishio; Hefin R Jones; Ronen Sumagin; Roland S Hilgarth; Ashfaqul Alam; Gabrielle Fredman; Ioannis Argyris; Emile Rijcken; Dennis Kusters; Chris Reutelingsperger; Mauro Perretti; Charles A Parkos; Omid C Farokhzad; Andrew S Neish; Asma Nusrat
Journal:  J Clin Invest       Date:  2015-02-09       Impact factor: 14.808

Review 4.  Emerging roles of extracellular vesicles in neurodegenerative disorders.

Authors:  Yang You; Tsuneya Ikezu
Journal:  Neurobiol Dis       Date:  2019-06-20       Impact factor: 5.996

Review 5.  Extracellular vesicles as potential biomarkers for alcohol- and drug-induced liver injury and their therapeutic applications.

Authors:  Young-Eun Cho; Byoung-Joon Song; Mohammed Akbar; Moon-Chang Baek
Journal:  Pharmacol Ther       Date:  2018-04-03       Impact factor: 12.310

Review 6.  Apoptosis and apoptotic body: disease message and therapeutic target potentials.

Authors:  Xuebo Xu; Yueyang Lai; Zi-Chun Hua
Journal:  Biosci Rep       Date:  2019-01-18       Impact factor: 3.840

7.  Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors.

Authors:  Dawei Liu; Xiaoxing Kou; Chider Chen; Shiyu Liu; Yao Liu; Wenjing Yu; Tingting Yu; Ruili Yang; Runci Wang; Yanheng Zhou; Songtao Shi
Journal:  Cell Res       Date:  2018-07-20       Impact factor: 25.617

8.  Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing.

Authors:  Veronika Butin-Israeli; Triet M Bui; Hannah L Wiesolek; Lorraine Mascarenhas; Joseph J Lee; Lindsey C Mehl; Kaitlyn R Knutson; Stephen A Adam; Robert D Goldman; Arthur Beyder; Lisa Wiesmuller; Stephen B Hanauer; Ronen Sumagin
Journal:  J Clin Invest       Date:  2019-01-14       Impact factor: 14.808

9.  Extracellular Vesicles: Evolving Contributors in Autoimmunity.

Authors:  Stergios Katsiougiannis
Journal:  For Immunopathol Dis Therap       Date:  2015

10.  Cytokine-induced release of ceramide-enriched exosomes as a mediator of cell death signaling in an oligodendroglioma cell line.

Authors:  Maria Podbielska; Zdzisław M Szulc; Ewa Kurowska; Edward L Hogan; Jacek Bielawski; Alicja Bielawska; Narayan R Bhat
Journal:  J Lipid Res       Date:  2016-09-13       Impact factor: 5.922
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