Literature DB >> 24535316

Ultrasonographic features of fibrous hamartoma of infancy.

Seungsoo Lee1, Young-Hun Choi, Jung-Eun Cheon, Myung-Joon Kim, Mi-Jung Lee, Myoung Ju Koh.   

Abstract

OBJECTIVE: To review imaging features of fibrous hamartoma of infancy (FHI), focusing on ultrasonography (US) findings.
MATERIALS AND METHODS: We retrospectively reviewed pediatric patients who were diagnosed with pathologically confirmed FHI in two children's hospitals from 2004 to 2013. Imaging features of US, Doppler US, and magnetic resonance imaging (MRI) were evaluated.
RESULTS: Thirteen pediatric patients (M:F = 7:6; age 5-22 months, mean 11.3 months) were included. Mean lesion size was 3.2 cm (range, 0.7-8.0 cm). The tumors were located in the back (n = 4), scrotum (n = 2), scalp, shoulder, axilla, forearm, intergluteal cleft, inguinal area, and thigh. US was performed in 11 patients. With the exception of two scrotal masses, all masses were located in the dermal and subcutaneous layer. All masses demonstrated heterogeneous hyperechogenicity with a "serpentine pattern" of intervening hypoechoic portions in the hyperechoic mass. The margins were ill-defined (n = 9) or lobulated (n = 2). Doppler US was performed in nine patients and showed no (n = 6) or minimal (n = 3) vascularity. MRI was performed in five patients and the masses showed heterogeneous signal intensity with the presence of fat on T1- and T2-weighted images.
CONCLUSIONS: FHI is a tumor that is typically located in the dermal and subcutaneous layer in young children less than 2 years old and presents as a heterogeneously hyperechoic mass with a "serpentine pattern" and ill-defined or lobulated margin on US and no remarkable vascularity on Doppler US.

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Mesh:

Year:  2014        PMID: 24535316     DOI: 10.1007/s00256-014-1838-1

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  19 in total

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Authors:  J Lin; J A Jacobson; D P Fessell; W J Weadock; C W Hayes
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2.  Fibrous hamartoma of infancy at the wrist and the use of MRI in preoperative planning.

Authors:  N Ashwood; J D Witt; M A Hall-Craggs
Journal:  Pediatr Radiol       Date:  2001-06

3.  FIBROUS HAMARTOMA OF INFANCY.

Authors:  F M ENZINGER
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Review 4.  Fibrous hamartoma of infancy.

Authors:  D M Scott; J R Peña; E F Omura
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Review 5.  Pediatric soft-tissue tumors and pseudotumors: MR imaging features with pathologic correlation: part 2. Tumors of fibroblastic/myofibroblastic, so-called fibrohistiocytic, muscular, lymphomatous, neurogenic, hair matrix, and uncertain origin.

Authors:  Eoghan E Laffan; Bo-Yee Ngan; Oscar M Navarro
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6.  Congenital fibrous hamartoma of the knee.

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7.  Role of ultrasound in the diagnosis of common soft tissue lesions of the limbs.

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Review 8.  Subdermal fibrous hamartoma of infancy: pathology of 40 cases and differential diagnosis.

Authors:  C Sotelo-Avila; P M Bale
Journal:  Pediatr Pathol       Date:  1994 Jan-Feb

9.  Fibrous hamartoma of infancy: an immunohistochemical and ultrastructural study.

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Journal:  Hum Pathol       Date:  1991-09       Impact factor: 3.466

10.  Fibrous tumours in children: imaging features of a heterogeneous group of disorders.

Authors:  G F Eich; J C Hoeffel; H Tschäppeler; I Gassner; U V Willi
Journal:  Pediatr Radiol       Date:  1998-07
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  6 in total

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4.  Scrotal fibrous hamartoma of infancy: A case report and literature review of a rare tumor of the genitourinary tract.

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Review 5.  Ultrasonography of Pediatric Superficial Soft Tissue Tumors and Tumor-Like Lesions.

Authors:  Hae Won Kim; So Young Yoo; Saelin Oh; Tae Yeon Jeon; Ji Hye Kim
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6.  A rare cause of unilateral breast swelling in a male infant caused by fibrous hamartoma of infancy combined with pseudoangiomatous stromal hyperplasia.

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  6 in total

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